Predicting Lamina Propria Invasion in Patients with Nonmuscle-invasive Bladder Cancer: Do RDW and NLR Really Work?

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Küçük Resim

Tarih

2019

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Objective: To determine the role of preoperative neutrophil-to-lymphocyte ratio (NLR) and red cell distribution width (RDW) in predicting lamina propria invasion in bladder cancer. Materials and Methods: Eighty-eight patients with non-muscle-invasive bladder cancer were evaluated retrospectively. The patients were divided into those with Ta tumors (group 1: n=36) and those with T1 tumors (group 2: n=52). For each patient, white blood cell, neutrophil, and leukocyte counts and RDW values were evaluated. Results: NLR was significantly lower in patients with Ta tumors. In addition, NLR below 3.22 was associated with 80.6% probability of Ta disease. RDW sensitivity in Ta non-muscle-invasive bladder tumors was much higher compared to T1 tumors. RDW below 15.35 was associated with 94.4% probability of Ta disease. Conclusion: NLR and RDW are basic blood parameters that physicians can assess easily. Our results indicate that a combination of NLR and RDW can help clinicians predict lamina propria invasion in non-muscle-invasive bladder tumors.

Açıklama

Anahtar Kelimeler

Bladder cancer, Superficial, Lamina propria, Invasion

Kaynak

Üroonkoloji Bülteni

WoS Q Değeri

N/A

Scopus Q Değeri

Cilt

18

Sayı

1

Künye

Musa Ekici, M. D., Cemil Aydın, M. D., & Ersan Arda, M. D. (2019). Predicting Lamina Propria Invasion in Patients with Non-muscle-invasive Bladder Cancer: Do RDW and NLR Really Work?. Bull Urooncol, 18, 6-9.