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    Fabrication and characterization of gold-nanoparticles/chitosan film: A scaffold for L929-fibroblasts
    (2013) Türk, Mustafa; Tamer, Uğur; Alver, Erol; Çiftçi, Hakan; Metin, Ayşegül Ülkü; Karahan, Siyami
    The objective of the present study was to fabricate a gold nanoparticle crosslinked chitosan (Ch/AuNPs) composite film simple and to evaluate its use as a carrier matrix for L929- fibroblasts. L929- fibroblasts were seeded either onto Ch or Ch/AuNPs scaffolds. The Ch/AuNPs scaffold exhibited a higher cell proliferation and growth rate. The cytotoxicity test determined trypan blue staining indicated that Ch scaffolds devoid of AuNPs expressed almost no toxicity while the Ch/AuNPs composite scaffolds expressed a very limited toxicity only at higher doses. The Ch/AuNPs scaffold promotes cell attachment, growth and proliferation with almost no cytotoxicity. © 2013 Informa Healthcare USA, Inc.