Fabrication and characterization of gold-nanoparticles/chitosan film: A scaffold for L929-fibroblasts

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Tarih

2013

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

The objective of the present study was to fabricate a gold nanoparticle crosslinked chitosan (Ch/AuNPs) composite film simple and to evaluate its use as a carrier matrix for L929- fibroblasts. L929- fibroblasts were seeded either onto Ch or Ch/AuNPs scaffolds. The Ch/AuNPs scaffold exhibited a higher cell proliferation and growth rate. The cytotoxicity test determined trypan blue staining indicated that Ch scaffolds devoid of AuNPs expressed almost no toxicity while the Ch/AuNPs composite scaffolds expressed a very limited toxicity only at higher doses. The Ch/AuNPs scaffold promotes cell attachment, growth and proliferation with almost no cytotoxicity. © 2013 Informa Healthcare USA, Inc.

Açıklama

Anahtar Kelimeler

Chitosan, Cytotoxicity, Gold Nanorod, L929- Fibroblasts

Kaynak

Artificial Cells, Nanomedicine and Biotechnology

WoS Q Değeri

N/A

Scopus Q Değeri

Q1

Cilt

41

Sayı

6

Künye

Türk, M., Tamer, U., Alver, E., Çiftçi, H., Metin, A. Ü., Karahan, S. (2013). Fabrication and characterization of gold-nanoparticles/chitosan film: a scaffold for L929-fibroblasts. Artificial Cells, Nanomedicine and Biotechnology, 41(6), 395-401.