SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL PROPERTIES OF INTERCALATED KAOLINITE NANOCLAYS: INTERCALATION AND BIOCOMPATIBILITY
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Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Sciendo
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The aims of the present study were to synthesize the intercalated kaolinite samples with dimethylsulfoxide (DMSO), glutamic acid (GA), succinimide (SIM), cetylpyridiniumchloride (CPC), and hexadecyltrimethylammoniumchloride (HDTMA(+)); to characterize by X-ray diffraction (XRD), Brunauer-Emmett-Teller (BET), scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier transform infrared spectroscopy-attenuated total reflectance (FTIR-ATR), and to determine the hemocompatibility and the cytotoxic effects of the intercalated kaolinite nanoclays on human lymphocytes. It was found that the intercalation with DMSO did not cause any decrease in cell viability until its maximum concentration (500 mu g/mL), however, the intercalation with SIM, CPC, and (HDTMA(+)) causd important decreases in lymphocyte viabilities. It was determined that no significant decrease was observed in protein content of the lymphocyte cells exposed to the kaolinite nanoclays except the ones intercalated with SIM. Furthermore, the pristine kaolinite nanoclays which were intercalated with DMSO, GA, and SIM exhibited high hemocompatibility and the nanoclays intercalated with CPC and (HDTMA(+)) were highly hemocompatibile for the amounts below 125 and 500 mu g/mL, respectively. All the results of this work can serve for the human risk assesment of intercalated nanoclays.
Açıklama
Anahtar Kelimeler
Intercalated kaolinite nanoclay, cytotoxicity, hemocompatibility
Kaynak
Advances In Materials Science
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
19
Sayı
1
