Is it important to see the coexistent seminal vesicle invasion and extracapsular extension at the radical prostatectomy specimen reports?

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dc.contributor.authorTopuz, Sezgin
dc.contributor.authorÖzdeş, Cüneyt
dc.contributor.authorGökkaya, Cevdet Serkan
dc.contributor.authorTağcı, Süleyman
dc.contributor.authorAktaş, Binhan Kaan
dc.contributor.authorBulut, Süleyman
dc.contributor.authorBaykam, Mehmet Murat
dc.date.accessioned2021-11-01T18:18:49Z
dc.date.available2021-11-01T18:18:49Z
dc.date.issued2020
dc.department[Belirlenecek]
dc.description.abstractAim: To evaluate the effect of coexistent extracapsular extension and seminal vesicle invasion on biochemical reccurence free survival rates in patients who had undergone open radical retropubic prostatectomy. Material and Methods: The data of 307 patients with clinically localized prostate cancer who had undergone radical retropubic prostatectomy between January 2000 and May 2019 were evaluated retrospectively. According to extension of tumor on surgical specimens, patients were classified into five groups as; organ-confined disease, extracapsular extension, isolated seminal vesicle invasion, extracapsular extension in addition to seminal vesicle invasion and lymph node involvement. Patient groups were analyzed categorically with regard to biochemical reccurence free survival rates by using Kaplan Meier analysis, log-rank and chi-square tests. The effect of pathological features of surgical specimens on biochemical reccurence was evaluated by using univariate and multivariate Cox regression analysis. Results: There were statistically significant differences on biochemical reccurence free survival rates among the five groups, and pathological stage and biochemical reccurence rates increased correspondingly. Multivariate Cox regression analysis showed that coexistent extracapsular extension and seminal vesicle invasion, and lymph node involvement are the two significant factors that negatively effect the biochemical reccurence free survival rate. Conclusion: Coexistence of extracapsular extension and seminal vesicle invasion is a worse prognostic factor compared to their isolated forms.
dc.identifier.doi10.5455/annalsmedres.2019.04.314
dc.identifier.endpage1625en_US
dc.identifier.issn2636-7688
dc.identifier.issn2636-7688
dc.identifier.issue6en_US
dc.identifier.startpage1621en_US
dc.identifier.urihttps://doi.org10.5455/annalsmedres.2019.04.314
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TXpneU16STRPQT09
dc.identifier.urihttps://hdl.handle.net/11491/8191
dc.identifier.volume27en_US
dc.indekslendigikaynakTR-Dizin
dc.institutionauthor[Belirlenecek]
dc.language.isoen
dc.relation.ispartofAnnals of Medical Research
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subject[No Keywords]en_US
dc.titleIs it important to see the coexistent seminal vesicle invasion and extracapsular extension at the radical prostatectomy specimen reports?
dc.typeArticle

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