The predictive value of neutrophil-lymphocyte ratio and mean platelet volume in patients with colorectal carcinoma

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dc.contributor.authorKöseoğlu, Hüseyin
dc.contributor.authorAkar, Mustafa
dc.contributor.authorSarı, Sevil Özer
dc.contributor.authorSolakoğlu, Tevfik
dc.contributor.authorPolat, Yunus Halil
dc.contributor.authorTahtacı, Mustafa
dc.contributor.authorErsoy, Osman
dc.date.accessioned2021-11-01T18:18:49Z
dc.date.available2021-11-01T18:18:49Z
dc.date.issued2020
dc.department[Belirlenecek]
dc.description.abstractAim: This study aimed to investigate neutrophil-lymphocyte ratio (NLR) and mean platelet volume (MPV) for predicting colorectal cancer (CRC). Material and Methods: We investigated retrospectively patients who underwent colonoscopy. The study consisted of 75 patients with CRC and 91 study participants with normal colonoscopy as control group, and MPV and NLR were compared between groups. MPV and NLR were also investigated for tumor stage and metastasis. Results: Among the CRC patients the mean NLR value (3.09 vs 2.26) and PLT count (287080 vs 251857) were significantly higher, whereas the mean MPV (9.62 vs 10.68 fL) and hemoglobin level (11.62 vs 14.18 g/dl) were significantly lower in the CRC group. WBC count was not significantly different between the groups. Mean NLR in metastatic patients and non-metastatic patients were 3.56 and 2.73, respectively (p:0.01). Conclusion: We showed that high NLR and low MPV are associated with CRC. Elevated NLR is related with presence of CRC and it can be used for risk prediction. Although we found lower MPV levels, conflicting results about MPV in CRC prevents it from using as a marker in CRC.
dc.identifier.doi10.5455/annalsmedres.2020.03.277
dc.identifier.endpage1667en_US
dc.identifier.issn2636-7688
dc.identifier.issn2636-7688
dc.identifier.issue6en_US
dc.identifier.startpage1663en_US
dc.identifier.urihttps://doi.org10.5455/annalsmedres.2020.03.277
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TXpneU5Ua3pNdz09
dc.identifier.urihttps://hdl.handle.net/11491/8192
dc.identifier.volume27en_US
dc.indekslendigikaynakTR-Dizin
dc.institutionauthor[Belirlenecek]
dc.language.isoen
dc.relation.ispartofAnnals of Medical Research
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subject[No Keywords]en_US
dc.titleThe predictive value of neutrophil-lymphocyte ratio and mean platelet volume in patients with colorectal carcinoma
dc.typeArticle

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