Low Serum Magnesium Level Can be a Risk Factor for Retinopathy in Diabetic Patients: A Cross-Sectional Controlled Study

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dc.authoridCevher, Selim / 0000-0002-7968-4876
dc.authoridBankir, Mehmet / 0000-0003-3284-2838
dc.authoridSAHINOGLU-KESKEK, NEDIME / 0000-0001-8544-103X
dc.authoridKeskek, Sakir Ozgur / 0000-0001-5888-3123
dc.authorwosidSAHINOGLU-KESKEK, NEDIME / T-4258-2017
dc.contributor.authorBankir, Mehmet
dc.contributor.authorKeskek, Nedime Sahinoglu
dc.contributor.authorSaler, Tayyibe
dc.contributor.authorKeskek, Sakir Ozgur
dc.contributor.authorCevher, Selim
dc.date.accessioned2021-11-01T15:05:38Z
dc.date.available2021-11-01T15:05:38Z
dc.date.issued2021
dc.department[Belirlenecek]
dc.description.abstractAim: Uncontrolled diabetes can lead to complications which are related to high blood sugar and insulin resistance (IR). A decrease in serum magnesium (Mg) levels can cause an increase in IR and a worsening of glycaemic control. In this study, we aimed to investigate the relationship between diabetic retinopathy (DR) and serum Mg levels. Methods: The study was designed as a cross-sectional study in the internal medicine department of a tertiary referral center (Adana Numune Training and Research Hospital) in Turkey. A total of 554 subjects, including 176 patients with DR patients, 209 patients without DR, and 169 healthy individuals were included in this study. Serum fasting glucose levels, insulin levels, homeostasis model assessment of insulin resistance (HOMA-IR), HbA1c percentages, and Mg levels were measured for all subjects. Results: Serum Mg level was lower in patients with DR (p<0.001). Furthermore; HOMA-IR, HbA1c and fasting glucose levels were higher in patients with DR (p<0.001, respectively). Incidence of DR was associated with serum Mg levels (odds ratio: 2.1, confidence interval: 95% 1.2-3.6, p=0.005). Conclusion: Low Mg level can lead to retinopathy by impairing glucose homeostasis. In patients with diabetes, Mg levels should be checked since Mg may be a supporting treatment.
dc.identifier.doi10.4274/haseki.galenos.2021.7188
dc.identifier.endpage344en_US
dc.identifier.issn1302-0072
dc.identifier.issn2147-2688
dc.identifier.issue4en_US
dc.identifier.startpage340en_US
dc.identifier.urihttps://doi.org/10.4274/haseki.galenos.2021.7188
dc.identifier.urihttps://hdl.handle.net/11491/7353
dc.identifier.volume59en_US
dc.identifier.wosWOS:000692326800013
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.institutionauthor[Belirlenecek]
dc.language.isoen
dc.publisherGalenos Yayincilik
dc.relation.ispartofHaseki Tip Bulteni-Medical Bulletin Of Haseki
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDiabetic retinopathyen_US
dc.subjecthyperglycemiaen_US
dc.subjectinsulin resistanceen_US
dc.subjectmagnesiumen_US
dc.subjecttype 2 diabetes mellitusen_US
dc.titleLow Serum Magnesium Level Can be a Risk Factor for Retinopathy in Diabetic Patients: A Cross-Sectional Controlled Study
dc.typeArticle

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