Determination of colistin resistance in Escherichia coli isolates from foods in Turkey, 2011-2015

dc.contributor.authorGüzel, Mustafa
dc.contributor.authorAvşaoğlu, M. Dilek
dc.contributor.authorSoyer, Yeşim
dc.date.accessioned2021-11-01T18:18:46Z
dc.date.available2021-11-01T18:18:46Z
dc.date.issued2020
dc.department[Belirlenecek]
dc.description.abstractAntimicrobial resistance of pathogenic microorganisms is an emerging public health concern. Intensive use of antibiotics in food animals might increase antimicrobial resistance in foodborne pathogens. Colistin is a last resort antibiotic for treatment of multidrug resistant (MDR) Gram negative pathogens. The recent antimicrobial resistance studies revealed a mobile antimicrobial resistance gene (mcr) that provides resistance to colistin. Furthermore, the gene has been found in different genera. Therefore, the aim of this study was to determine colistin resistance of Escherichia coli isolates (N=48) isolated in between 2011 and 2015 from food samples in Turkey. In addition, 5 mcr genes and their variants were screened by performing PCR on resistant isolates. 4 E. coli isolates were found resistant to colistin above the epidemiological cut-off value (Minimum inhibitory concentration (MIC) > 2mg/L). None of the resistant isolates had the mcr genes. Further studies with human and food isolates should be conducted to figure out which gene or genes are responsible for colistin resistance.
dc.identifier.doi10.3153/FH20017
dc.identifier.endpage169en_US
dc.identifier.issn2602-2834
dc.identifier.issn2602-2834
dc.identifier.issue3en_US
dc.identifier.startpage160en_US
dc.identifier.urihttps://doi.org10.3153/FH20017
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TXpnNE16ZzRPQT09
dc.identifier.urihttps://hdl.handle.net/11491/8177
dc.identifier.volume6en_US
dc.indekslendigikaynakTR-Dizin
dc.institutionauthor[Belirlenecek]
dc.language.isoen
dc.relation.ispartofFood and Health
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subject[No Keywords]en_US
dc.titleDetermination of colistin resistance in Escherichia coli isolates from foods in Turkey, 2011-2015
dc.typeArticle

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