Tribological properties of PVA/PVP blend hydrogels against articular cartilage

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dc.authoridDini, Daniele / 0000-0002-5518-499X
dc.authoridKanca, Yusuf / 0000-0002-8769-0774
dc.authoridMilner, Piers / 0000-0002-4299-773X
dc.authorwosidDini, Daniele / H-8335-2013
dc.authorwosidKanca, Yusuf / AAP-2466-2021
dc.contributor.authorKanca, Yusuf
dc.contributor.authorMilner, Piers
dc.contributor.authorDini, Daniele
dc.contributor.authorAmis, Andrew A.
dc.date.accessioned2021-11-01T15:01:48Z
dc.date.available2021-11-01T15:01:48Z
dc.date.issued2018
dc.department[Belirlenecek]
dc.description.abstractThis research investigated in-vitro tribological performance of the articulation of cartilage-on-polyvinyl alcohol (PVA) and polyvinyl pyrrolidone (PVP) blend hydrogels using a custom-designed multi-directional wear rig. The hydrogels were prepared by repeated freezing-thawing cycles at different concentrations and PVA to PVP fractions at a given concentration. PVA/PVP blend hydrogels showed low coefficient of friction (COF) values (between 0.12 +/- 0.01 and 0.14 +/- 0.02) which were closer to the cartilage-on-cartilage articulation (0.03 +/- 0.01) compared to the cartilage-on-stainless steel articulation (0.46 +/- 0.06). The COF increased with increasing hydrogel concentration (p = 0.03) and decreasing PVP content at a given concentration (p < 0.05). The cartilage-on-hydrogel tests showed only the surface layers of the cartilage being removed (average volume loss of the condyles was 12.5 +/- 4.2 mm(3)). However, the hydrogels were found to be worn/deformed. The hydrogels prepared at a higher concentration showed lower apparent volume loss. A strong correlation (R-2 = 0.94) was found between the COF and compressive moduli of the hydrogel groups, resulting from decreasing contact congruency. It was concluded that the hydrogels were promising as hemiarthroplasty materials, but that improved mechanical behaviour was required for clinical use.
dc.description.sponsorshipMinistry of National Education of TurkeyMinistry of National Education - Turkeyen_US
dc.description.sponsorshipThis study was funded by the Ministry of National Education of Turkey.en_US
dc.identifier.doi10.1016/j.jmbbm.2017.10.027
dc.identifier.endpage45en_US
dc.identifier.issn1751-6161
dc.identifier.issn1878-0180
dc.identifier.pmid29132099
dc.identifier.startpage36en_US
dc.identifier.urihttps://doi.org/10.1016/j.jmbbm.2017.10.027
dc.identifier.urihttps://hdl.handle.net/11491/6689
dc.identifier.volume78en_US
dc.identifier.wosWOS:000423247700005
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.institutionauthor[Belirlenecek]
dc.language.isoen
dc.publisherElsevier Science Bv
dc.relation.ispartofJournal Of The Mechanical Behavior Of Biomedical Materials
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCartilageen_US
dc.subjectHemiarthroplastyen_US
dc.subjectHydrogelen_US
dc.subjectTribologyen_US
dc.subjectMechanical propertiesen_US
dc.titleTribological properties of PVA/PVP blend hydrogels against articular cartilage
dc.typeArticle

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