Synthesis and biological activity of new cycloalkylthiophene-Schiff bases and their Cr(III) and Zn(II) complexes
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Tarih
2010
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Birkhauser Boston
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
A series of some novel Ethyl 2-((1-hydroxynaphthalen-2-yl)methyleneamino)- 5,6-dihydro-4H-cyclopenta[b]thiopehene-3-carboxylate, Ethyl 2-((1- hydroxynaphthalen- 2-yl)methyleneamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3- carboxylate, Ethyl 2-((1-hydroxynaphtalen-2-yl)methyleneamino)-5,6,7,8- tetrahydro-4H-cyclohepta [b]thiophene-3-carboxylate and their Cr(III) and Zn(II) complexes have been synthesized. All of these substances have been examined for antibacterial activity against pathogenic strains Listeria monocytogenes 4b (ATCC-19115), Staphylococcus aureus (ATCC25923), Proteus OX2 Wrah (ETS.40-A-4), Escherichia coli (ATCC-1280), Salmonella typhi H (NCTC-901.8394), Pseudomonas putida sp., Brucella abortus (A.99, UK-1995) RSKK-03026. Sh. boydii type 11 (Pasteur51.6), Sh. boydii type 16 (cHe 67.11), Sh. boydii type 6 (RSKK-96043), and antifungal activity against Candida albicans (Y-1200-NIH, Tokyo). Some of the compounds exhibited activity comparable to ampicillin ofloxacin, nystatin, kanamycin, sulphamethoxazol, amoxycillin, and chloroamphenicol. Most of the studied compounds were found effective against bacteria studied and yeast. © Birkhäuser Boston 2009.
Açıklama
Anahtar Kelimeler
Antimicrobial Activity, Cycloalkylthiophenes, Drug, Gewald Methods, Schiff Bases, Sulfur
Kaynak
Medicinal Chemistry Research
WoS Q Değeri
N/A
Scopus Q Değeri
Q1
Cilt
19
Sayı
6
Künye
Altundaş, A., Sarı, N., Çolak, N., Öğütcü, H. (2010). Synthesis and biological activity of new cycloalkylthiophene-Schiff bases and their Cr (III) and Zn (II) complexes. Medicinal Chemistry Research, 19(6), 576-588.
