Could 25-oh Vitamin D deficiency be a reason for hpv infection persistence in cervical premalignant lesions?

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dc.authorid0000-0002-8444-9694
dc.authorid0000-0001-6946-4995
dc.authorid0000-0002-7869-9662
dc.contributor.authorÖzgü, Emre
dc.contributor.authorYılmaz, Nafiye
dc.contributor.authorBaşer, Eralp
dc.contributor.authorGüngör, Tayfun
dc.contributor.authorErkaya, Salim
dc.contributor.authorYakut, Halil İbrahim
dc.date.accessioned2019-05-13T09:03:37Z
dc.date.available2019-05-13T09:03:37Z
dc.date.issued2016
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractVitamin D is an essential precursor to the steroid hormone calcitriol which mainly regulates calcium homeostasis. Moreover anti-proliferative, proapoptotic, anti-angiogenic effects of Vitamin D support the ideas of preventive role in various cancer. This study aimed to determine if there is a relationship between HPVDNA infection and cervical intraepithelial neoplasia and Vitamin D deficiency. As a result of the study the difference of 25-OH Vitamin D3 levels between HPVDNA positive group and the control group were statistically significant (p=0,009). According to results of our study, with the proven anti-inflammatory functions of Vitamin D, the deficiency of these molecule and its metabolites can be a possible reason for HPVDNA persistence and related cervical intraepithelial neoplasia. © 2016 Old City Publishing, Inc. © 2016 Old City Publishing, Inc.
dc.identifier.citationOzgu, E., Yilmaz, N., Baser, E., Gungor, T., Erkaya, S., & Yakut, H. I. (2016). Could 25-oh vitamin D deficiency be a reason for HPV infection persistence in cervical premalignant lesions. J. Exp. Ther. Oncol, 11, 177-180.
dc.identifier.endpage180en_US
dc.identifier.issn1359-4117
dc.identifier.issue3en_US
dc.identifier.scopusqualityN/A
dc.identifier.startpage177en_US
dc.identifier.urihttps://hdl.handle.net/11491/1504
dc.identifier.volume11en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherOld City Publishing
dc.relation.ispartofJournal of Experimental Therapeutics and Oncology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCervical Intraepithelial Lesionsen_US
dc.subjectCholecalciferolen_US
dc.subjectHPVen_US
dc.subjectVitamin Den_US
dc.titleCould 25-oh Vitamin D deficiency be a reason for hpv infection persistence in cervical premalignant lesions?
dc.typeArticle

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