The role of grape seed extract in the effect of swimming exercises on epilepsy

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dc.authorid0000-0001-5976-7503
dc.contributor.authorSoslu, Recep
dc.contributor.authorTutkun, Erkut
dc.contributor.authorKartal, Alpaslan
dc.contributor.authorÇıplak, Mustafa Ertuğrul
dc.contributor.authorÇekin, Resul
dc.contributor.authorKamuk, Yetkin Utku
dc.date.accessioned2019-05-13T09:02:31Z
dc.date.available2019-05-13T09:02:31Z
dc.date.issued2013
dc.departmentHitit Üniversitesi, Spor Bilimleri Fakültesi, Antrenörlük Eğitimi Bölümü
dc.description.abstractGrape seed extract (GSE) is one of the strongest known antioxidants. GSE actively prevents the formation of free radicals and assists in their elimination. Our aim was to investigate the effects on epileptiform activity of GSE administered concurrently with swimming exercises. A total of 35 male albino Wistar rats were used in this study. Epileptiform activity was induced in rats through the injection of penicillin (500 IU) into the left cerebral cortex. Thirty minutes after the application of penicillin, 200 mg/kg of GSE dissolved in normal saline was administered intraperitoneally. Based on the results of the statistical analysis, a significant decrease in spike frequency was observed after 60 minutes in the 15-minute group (67%), after 40 minutes in the 30-minute group (43%), and after 40 minutes in the 60-minute group (42%), while no significant decrease was identified in the amplitude values of the groups. According to the study results, in rats performing short-, medium-, and long-term swimming exercises, GSE administration allowed epileptiform activity to decrease within a shorter period of time. Thus, patients with epilepsy can potentially perform swimming exercises more safely by regularly using antioxidant substances.
dc.identifier.citationSoslu, R., Tutkun, E., Kartal, A., Çıplak, M. E., Çekin, R., Kamuk, Y. U. (2013). The role of grape seed extract in the effect of swimming exercises on epilepsy. Life Science Journal, 10(4), 648-653.
dc.identifier.endpage653en_US
dc.identifier.issn1097-8135
dc.identifier.issue4en_US
dc.identifier.scopusqualityN/A
dc.identifier.startpage648en_US
dc.identifier.urihttps://hdl.handle.net/11491/1271
dc.identifier.volume10en_US
dc.indekslendigikaynakScopus
dc.language.isoen
dc.relation.ispartofLife Science Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectEpilepsyen_US
dc.subjectGrape Seed Extracten_US
dc.subjectRat Swimming Exerciseen_US
dc.titleThe role of grape seed extract in the effect of swimming exercises on epilepsy
dc.typeArticle

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