Spectrophotometric determination of acidity constants of some novel methotrexate-like compounds in water and acetonitrile-water binary mixtures
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Tarih
2010
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The acidity constants of four novel methotrexate like compounds (NPALA; (N-[4-[[2-hydroxy -1-naphtyl)methylene]amino]benzoyl-?-alanin) TPALA; (N-[4-(2-thiophene-aldiminobenzoyl)-?-alanin), SAL-ALA; N-[4-[[2-hydroxyphenyl)methylene]amino]benzoyl-?-alanin], MeO-SAL-ALA; (N-[4-[[(2-hydroxy-4-methoxyphenyl)metylene]amino]benzoyl-?-alanin)) have been determined in water and acetonitrile-water binary mixtures (10%, and 20% (v/v)) by spectrophotometric method. The effect of the acetonitrile concentration on the ionization constant was also studied.
Açıklama
Anahtar Kelimeler
Acetonitrile-Water Mixtures, Acidity Constants, Methotrexate, Spectroscopic Method
Kaynak
Reviews in Analytical Chemistry
WoS Q Değeri
N/A
Scopus Q Değeri
Q1
Cilt
29
Sayı
03.Apr
Künye
Çolak, N., Şanlı, S., Şanlı, N. (2010). Spectrophotometric determination of acidity constants of some novel methotrexate-like compounds in water and acetonitrile-water binary mixtures. Reviews in Analytical Chemistry, 29(3), 241-253.
