Facile synthesis of the azocino[4,3-b]indole framework of strychnopivotine and other Strychnos alkaloids
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Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer New York LLC
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
[Figure not available: see fulltext.]A new synthetic route to the 1,5-methanoazocino[4,3-b]indole is described. The aim of the present study is to provide a tetracyclic skeleton for the synthesis of pentacyclic Strychnos alkaloids (tubifolidine and strychnopivotine). Starting from a carbazole derivative, the ring closure was achieved by an intramolecular aldol reaction. The final product was obtained in 45% in the overall yield over 7 steps. © 2016, Springer Science+Business Media New York.
Açıklama
Anahtar Kelimeler
1,5-methanoazocino[4,3-b]indole, Strychnos Alkaloids
Kaynak
Chemistry of Heterocyclic Compounds
WoS Q Değeri
N/A
Scopus Q Değeri
Q3
Cilt
52
Sayı
3
Künye
Uludag, N., Yılmaz, R.K., Asutay, O., Çolak, N. (2016). Facile synthesis of the azocino[4,3-b]indole framework of strychnopivotine and other Strychnos alkaloids. Chemistry of Heterocyclic Compounds, 52(3), 196-199.