Facile synthesis of the azocino[4,3-b]indole framework of strychnopivotine and other Strychnos alkaloids

[ X ]

Tarih

2016

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Springer New York LLC

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

[Figure not available: see fulltext.]A new synthetic route to the 1,5-methanoazocino[4,3-b]indole is described. The aim of the present study is to provide a tetracyclic skeleton for the synthesis of pentacyclic Strychnos alkaloids (tubifolidine and strychnopivotine). Starting from a carbazole derivative, the ring closure was achieved by an intramolecular aldol reaction. The final product was obtained in 45% in the overall yield over 7 steps. © 2016, Springer Science+Business Media New York.

Açıklama

Anahtar Kelimeler

1,5-methanoazocino[4,3-b]indole, Strychnos Alkaloids

Kaynak

Chemistry of Heterocyclic Compounds

WoS Q Değeri

N/A

Scopus Q Değeri

Q3

Cilt

52

Sayı

3

Künye

Uludag, N., Yılmaz, R.K., Asutay, O., Çolak, N. (2016). Facile synthesis of the azocino[4,3-b]indole framework of strychnopivotine and other Strychnos alkaloids. Chemistry of Heterocyclic Compounds, 52(3), 196-199.