The Course of Renal Functions in COPD. Two Statition: Exacerbation and Stable Period

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dc.contributor.authorBaha, Ayşe
dc.contributor.authorOgan, Nalan
dc.contributor.authorAkpınar, Evrim Eylem
dc.contributor.authorAteş, Can
dc.contributor.authorGülhan, Meral
dc.date.accessioned2021-11-01T18:14:55Z
dc.date.available2021-11-01T18:14:55Z
dc.date.issued2019
dc.department[Belirlenecek]
dc.description.abstractOBJECTIVE: Comorbidities in chronic obstructive pulmonary disease (COPD) are important factors that determine the prognosis of the disease. However, there are few studies about renal dysfunction. We aimed to compare the renal functions in COPD patients with stable and exacerbation periods and to determine the frequency of acute renal failure (ARF) during exacerbation. MATERIALS AND METHODS: The files of 320 patients with COPD (forced expiratory volume in 1 s/forced vital capacity <70% in pulmonary function test) who were admitted to our hospital between 2015 and 2016 were evaluated retrospectively. After exclusion criteria, 113 patients were included in the study. Data were analyzed by appropriate statistical method. RESULTS: Ninety (80.4%) of the patients were male and 23 (19.6%) were female. In the exacerbation period, blood urea nitrogen (P < 0.001), creatinine (P < 0.001), white blood cell (P < 0.001), C?reactive protein (P < 0.001), and sedimentation (P < 0.001) were higher than that in the stable period. Furthermore, hemoglobin (P = 0.021) and estimated glomerular filtration rate (eGFR) (P < 0.001) were significantly lower. The number of emergency department admission in patients with eGFR <60 ml/min during the exacerbation more than the patients with eGFR ?60 ml/min. Twenty (17.7%) patients have developed ARF during exacerbation (eGFR <60 ml/min). CONCLUSION: In COPD exacerbation period, kidney function is affected negatively in most patients (even if it does not reach the ABY border) and tends to improve in the stable period. In patients with COPD, it is thought that the causes of respiratory failure negatively affect renal function.
dc.identifier.doi10.4103/ejop.ejop_28_19
dc.identifier.endpage68en_US
dc.identifier.issn2148-3620
dc.identifier.issn2148-5402
dc.identifier.issue1en_US
dc.identifier.startpage63en_US
dc.identifier.urihttps://doi.org10.4103/ejop.ejop_28_19
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TXpNd01UTTRPQT09
dc.identifier.urihttps://hdl.handle.net/11491/7583
dc.identifier.volume21en_US
dc.identifier.wosWOS:000466857400010
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.institutionauthor[Belirlenecek]
dc.language.isoen
dc.relation.ispartofEurasian Journal of Pulmonology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectSolunum Sistemien_US
dc.titleThe Course of Renal Functions in COPD. Two Statition: Exacerbation and Stable Period
dc.typeArticle

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