Does sufficient 25-hydroxyvitamin D mean lower metabolic risk for women?

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dc.authoridcetin, zeynep / 0000-0001-7824-4644
dc.contributor.authorCetin, Zeynep
dc.contributor.authorBaser, Ozden
dc.contributor.authorKoseoglu, Derya
dc.contributor.authorCatak, Merve
dc.date.accessioned2021-11-01T15:05:10Z
dc.date.available2021-11-01T15:05:10Z
dc.date.issued2020
dc.department[Belirlenecek]
dc.description.abstractOBJECTIVE: There are conflicting results regarding the relationship between metabolic diseases and vitamin D deficiency. We aimed to show the possible relationship between 25-hydroxy (OH) vitamin D levels and obesity, insulin resistance and hyperlipidemia in women. MATERIALS AND METHODS: Three hundred fifty seven female were included retrospectively. Body mass index (BMI) was determined with body weight (kg)/height (m(2)) formula. Fasting plasma glucose, insulin, lipid profile, calcium, phosphorus, parathormone, 25 hydroxy vitamin D, thyroid stimulating hormone were evaluated. Insulin resistance was calculated with homeostatic model values for insulin resistance (HOMA-IR). Patients were grouped according to 25 (OH) vitamin D levels and BMIs. RESULTS: 25 (OH) vitamin D was negative correlated with BMI, insulin and HOMA-IR, (respectively r = -0 .156, -0.128, -0.123 and p= 0.003, 0.015, 0.020). It is positive correlated with HDL and HDL/LDL ratio (respectively r= 0.183, 0.185 and p = 0.003, <0.001) HDL-C was higher in 25(OH) vitamin D sufficient group. After multivariate analysis, 25 (OH) vitamin D was still positively related with HDL and HDL/LDL ratio (respectively r= 0.127, 0.118 and p = <0.05). CONCLUSION: 25 (OH) Vitamin D is relationship with HDL, HDL/LDL ratio and invers relationship obesity. The normal 25 (OH) vitamin D supports the reduction of metabolik risk.
dc.identifier.doi10.3233/MNM-200432
dc.identifier.endpage318en_US
dc.identifier.issn1973-798X
dc.identifier.issn1973-7998
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85097670610
dc.identifier.scopusqualityQ3
dc.identifier.startpage311en_US
dc.identifier.urihttps://doi.org/10.3233/MNM-200432
dc.identifier.urihttps://hdl.handle.net/11491/7151
dc.identifier.volume13en_US
dc.identifier.wosWOS:000599237600002
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthor[Belirlenecek]
dc.language.isoen
dc.publisherIos Press
dc.relation.ispartofMediterranean Journal Of Nutrition And Metabolism
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subject25(OH) vitamin Den_US
dc.subjectobesityen_US
dc.subjectinsulin resistanceen_US
dc.subjectlipiden_US
dc.titleDoes sufficient 25-hydroxyvitamin D mean lower metabolic risk for women?
dc.typeArticle

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