Investigation of voltammetric behavior and electroanalytical determination of anticancer epirubicin via glassy carbon electrode using differential pulse and square wave voltammetry techniques

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dc.authorid0000-0002-7079-7604
dc.authorid0000-0003-2793-7154
dc.authorid0000-0001-7494-3077
dc.contributor.authorKurbanoğlu, Sevinç
dc.contributor.authorBozal Palabıyık, Burçin
dc.contributor.authorGümüştaş, Mehmet
dc.contributor.authorUslu, Bengi
dc.contributor.authorÖzkan, Sibel Ayşıl
dc.date.accessioned2019-05-10T09:39:15Z
dc.date.available2019-05-10T09:39:15Z
dc.date.issued2015
dc.departmentHitit Üniversitesi, Fen Edebiyat Fakültesi, Kimya Bölümü
dc.description.abstractThe electrochemical oxidation of epirubicin was investigated using cyclic, differential pulse and square wave voltammetry at glassy carbon electrode. The aim of the study was to determine epirubicin levels in pharmaceuticals via electrochemical methods. The oxidation process was quasi-reversible over the pH range studied and exhibited diffusion controlled electrode process. All experimental parameters have been optimized under the optimum conditions. The oxidation peak current was linearly proportional to the concentration of epirubicin in the range of 2×10-7-3.6×10-5 M with a detection limit of 4.1×10-8 M and 4.9×10-8 M by differential pulse and square wave voltammetry, respectively. These unique properties make the sensor suitable for the analysis of the trace amounts of epirubicin in pharmaceutical preparations. The proposed methods were applied to commercial preparations. Differential pulse and square wave voltammetry techniques were compared with t-test and F-test.
dc.identifier.citationKurbanoglu, S., Bozal-Palabiyik, B., Gumustas, M., Uslu, B., & Ozkan, S. A. (2015). Investigation of voltammetric behavior and electroanalytical determination of anticancer epirubicin via glassy carbon electrode using differential pulse and square wave voltammetry techniques. Rev. Roum. Chim., 60(5–6), 491-499.
dc.identifier.endpage499en_US
dc.identifier.issn0035-3930
dc.identifier.issue05.Junen_US
dc.identifier.scopusqualityQ4
dc.identifier.startpage491en_US
dc.identifier.urihttps://hdl.handle.net/11491/648
dc.identifier.volume60en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherEditions de l'Academie Republique Populaire
dc.relation.ispartofRevue Roumaine de Chimie
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subject[Belirlenecek]en_US
dc.titleInvestigation of voltammetric behavior and electroanalytical determination of anticancer epirubicin via glassy carbon electrode using differential pulse and square wave voltammetry techniques
dc.typeArticle

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