Elevated neutrophil-to-lymphocyte ratio in Bell's palsy and its correlation with facial nerve enhancement on MRI
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Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
SAGE Publications Inc.
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective. The aim of this study was to investigate the role of inflammation and atherothrombosis in Bell's palsy (BP) by using neutrophil-to-lymphocyte ratio (NLR) and mean platelet volume (MPV), respectively, and to study their relations with the facial nerve enhancement on temporal gadolinium-enhanced magnetic resonance imaging (TGd-MRI). Study Design. Case control study. Setting. Tertiary health institution. Subjects and Methods. This study was performed on 65 patients who were diagnosed with BP and a control group of 35 healthy individuals. The BP patients were also divided into 2 groups, those with facial nerve enhancement on TGd- MRI and those without enhancement. The NLR and MPV of each group were compared. Results. The NLRs of the BP patients were significantly higher than control group (P = .001). The NLRs of patients with facial nerve enhancement on TGd-MRI were significantly higher than patients without enhancement (P = .001). There was a positive and significant correlation between NLR and House-Brackmann (HB) grade of the patients (r = 0.641; P<.05). MPV did not show any significant correlation with any of the parameters studied (P .05). Conclusion. NLR can be used as a new and important marker in BP since it is high in BP patients and significantly correlated with HB grade and facial nerve enhancement on TGd- MR. On the other hand, MPV does not have such correlations. These results offer evidence to support an inflammatory theory rather than microvascular response theory in the etiopatogenesis of BP. © American Academy of Otolaryngology-Head and Neck Surgery Foundation 2014.
Açıklama
Anahtar Kelimeler
Bell's Palsy, Inflammation, Inflammatory Marker, Mean Platelet Volume, Neutrophil to Lymphocyte Ratio
Kaynak
Otolaryngology - Head and Neck Surgery (United States)
WoS Q Değeri
N/A
Scopus Q Değeri
Q1
Cilt
152
Sayı
1
Künye
Kum, R. O., Yurtsever Kum, N., Ozcan, M., Yilmaz, Y. F., Gungor, V., Unal, A., & Ciliz, D. S. (2015). Elevated neutrophil-to-lymphocyte ratio in Bell’s palsy and its correlation with facial nerve enhancement on MRI. Otolaryngology--Head and Neck Surgery, 152(1), 130-135.
