Thyroid nodules with atypia or follicular lesions of undetermined significance (AUS/FLUS): analysis of variables associated with outcome

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dc.contributor.authorKayılıoğlu, Selami Ilgaz
dc.contributor.authorDinç, Tolga
dc.contributor.authorSözen, İsa
dc.contributor.authorŞenol, Kazım
dc.contributor.authorKatar, Kağan
dc.contributor.authorKarabeyoğlu, Melih
dc.contributor.authorTez, Mesut
dc.contributor.authorCoşkun, Faruk
dc.date.accessioned2019-05-13T09:04:27Z
dc.date.available2019-05-13T09:04:27Z
dc.date.issued2014
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractBackground: The Bethesda System for Reporting Thyroid Cytopathology is one of the main classification systems for thyroid nodules. It expects that 7% of all fine needle aspiration biopsies will be reported as atypia or follicular lesions of undetermined significance, and 5-15% of these undetermined nodules are malignant. Our study is a retrospective analysis of variables that may be associated with outcome in patients with indeterminate thyroid nodules. Materials and Methods: Patients who underwent thyroidectomy in our institution between 2010 and 2014 were retrieved from the institutional records database. Patient demographics and medical histories were recorded. All ultrasonography reports were examined for nodule features and biochemical blood levels, hormone levels and complete blood counts were recorded. Results: A total of 103 patient cytopathology reports were regarded as belonging to the undetermined category. Some 35% of patients had malignant nodules. Median preoperative red cell distribution width (RDW) level was 13.6 inthe benign group, while it was 14.3 in patients with malignancy, demonstrating a significant correlation (p = 0.003). Only calcification presence was significantly different between benign and malignant groups on ultrasonography (p = 0.034). Conclusions: Ultrasonography is one of the primary tools for this matter. RDW levels may become another promising tool to predict malignancy.
dc.identifier.citationKayılıoğlu, S. I., Dinç, T., Sözen, İ., Şenol, K., Katar, K., Karabeyoğlu, M., Tez, M., Coşkun, F. (2014). Thyroid nodules with atypia or follicular lesions of undetermined significance (AUS/FLUS): analysis of variables associated with outcome. Asian Pacific Journal of Cancer Prevention, 15(23), 10307-10311.
dc.identifier.doi10.7314/APJCP.2014.15.23.10307
dc.identifier.endpage10311en_US
dc.identifier.issn1513-7368
dc.identifier.issue23en_US
dc.identifier.scopusqualityQ3
dc.identifier.startpage10307en_US
dc.identifier.urihttps://doi.org/10.7314/APJCP.2014.15.23.10307
dc.identifier.urihttps://hdl.handle.net/11491/1592
dc.identifier.volume15en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherAsian Pacific Organization for Cancer Prevention
dc.relation.ispartofAsian Pacific Journal of Cancer Prevention
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCytologyen_US
dc.subjectThyroid Neoplasmsen_US
dc.subjectThyroid Nodule Red Blood Cell Distribution Widthen_US
dc.titleThyroid nodules with atypia or follicular lesions of undetermined significance (AUS/FLUS): analysis of variables associated with outcome
dc.typeArticle

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