Impact of the COVID-19 Pandemic on CLABSI Rates and Antibiotic Resistance: A Multicenter Study in Türkiye

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dc.contributor.authorSargın-Altınok, E
dc.contributor.authorKeske, S
dc.contributor.authorBatırel, A
dc.contributor.authorBilgin, H
dc.contributor.authorGülten, E
dc.contributor.authorMenekşe, S
dc.contributor.authorGölbol, A
dc.contributor.authorKonya, P
dc.contributor.authorAltunal, LN
dc.contributor.authorÖzer, D
dc.contributor.authorAsan, A
dc.contributor.authorDeniz-Yüksel, A
dc.contributor.authorAkdoğan, Ö
dc.contributor.authorYanık-Yalçın, T
dc.contributor.authorAkgül, F
dc.contributor.authorAliravcı, İD
dc.contributor.authorKaragöz, T
dc.contributor.authorŞahin, A
dc.contributor.authorErdem, İ
dc.contributor.authorGürbüz, E
dc.contributor.authorYekta-Ürkmez, F
dc.contributor.authorKarakoç, ZÇ
dc.contributor.authorKaçmaz, B
dc.contributor.authorEren-Korkmaz, Ö
dc.contributor.authorKarslıoğlu, M
dc.contributor.authorArslan, M
dc.contributor.authorToygar-Deniz, M
dc.contributor.authorAydın, M
dc.contributor.authorDemirtürk, N
dc.contributor.authorAzap, A
dc.contributor.authorErgönül, Ö
dc.date.accessioned2026-03-31T13:21:21Z
dc.date.available2026-03-31T13:21:21Z
dc.date.issued2025
dc.description.abstractObjective: The COVID-19 pandemic significantly disrupted infection control practices in healthcare settings. Previous studies have reported increased rates of central line-associated bloodstream infections (CLABSI), particularly during the early stages and peak periods of the pandemic. This multicenter study aimed to evaluate the impact of the COVID-19 pandemic on CLABSI rates in T & uuml;rkiye over a four-year period from 2019 to 2022. Materials and Methods: We conducted a retrospective analysis of prospectively collected CLABSI data from hospitals across various regions of T & uuml;rkiye between 2019 and 2022. The study period was divided into three phases: pre-pandemic, early pandemic, and late pandemic. Demographic and clinical characteristics, mortality rates, and microbiological data were analyzed. Pathogen distribution and antibiotic resistance patterns were compared between the pre-pandemic and pandemic periods. Results: A total of 25 hospitals participated in the study. The CLABSI rates per 1000 catheter days were 4.26 in 2019, 4.13 in 2020, 3.68 in 2021, and 3.53 in 2022. Across all periods, 3238 pathogens were identified. Gram-negative bacteria predominated both before and during the pandemic, with Acinetobacter baumannii (18.6%) and Klebsiella pneumoniae (17.8%) being the most common. Notably, an increase in carbapenem and colistin resistance in K. pneumonia was observed during the pandemic compared to the pre-pandemic period. Conclusions: In T & uuml;rkiye, the predominant causative agents of CLABSI did not change during the pandemic, with Klebsiella spp. and A. baumannii being most frequently isolated. However, the rise in CLABSI-associated mortality during the pandemic highlights the broader impact of healthcare system disruptions.
dc.identifier.doi10.36519/idcm.2025.513
dc.identifier.issn2667-646X
dc.identifier.issue3
dc.identifier.pmid41111492
dc.identifier.urihttp://dx.doi.org/10.36519/idcm.2025.513
dc.identifier.urihttps://hdl.handle.net/11491/9708
dc.identifier.volume7
dc.identifier.wosWOS:001586743800006
dc.language.isoen
dc.publisherDOC DESIGN INFORMATICS CO LTD
dc.relation.ispartofINFECT DIS CLIN MICR
dc.subjectAntimicrobial resistance
dc.subjectCOVID-19 pandemic
dc.subjectcentral line-associated blood-stream infections
dc.subjecthealthcare-associated infections
dc.titleImpact of the COVID-19 Pandemic on CLABSI Rates and Antibiotic Resistance: A Multicenter Study in Türkiye
dc.typeArticle

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