Investigation of dna binding and cleavage activities of boron complexes in the presence of hydrogen peroxide
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Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Universitatea Babes-Bolyai, Catedra de Filosofie Sistematica
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Magnesium [di(hydroxy)mono(citratoborate)]dihydrate (Mg[B(Cit)(OH)2]2.2H2O), Lithium [di(hydroxy)mono(citratoborate)]hydrate Li[B(Cit)(OH)2].H2O, Sodium [di(hydroxy)mono(salicylato) borate)hydrate Na[B(Sal)(OH)2].H2O and Magnesium[bis(salicylatoborate)]decahydrate Mg[B(Sal)2]2.10H2O) complexes have been synthesized and characterized. The cattle genomic DNA (CG-DNA) interaction of the complexes was studied by spectroscopic methods, viscosity, and electrophoresis measurements. The complexes partially intercalated to CG-DNA. Furthermore, DNA cleavage activity of these complexes was also investigated using agarose gel electrophoresis and the complexes show moderate ability of cleavage to the DNA
Açıklama
Anahtar Kelimeler
Boron Complexes, DNA Cleavage, DNA-Binding Cleavage
Kaynak
Studia Universitatis Babes-Bolyai Chemia
WoS Q Değeri
N/A
Scopus Q Değeri
Q4
Cilt
59
Sayı
3
Künye
Devrim, A. K., Arslantaş, A., Sudağıdan, M., Köse, D. A., Karan, B. (2014). Investigation of dna binding and cleavage activities of boron complexes in the presence of hydrogen peroxide. Studia Universitatis Babes-Bolyai Chemia, 59(3), 109-118.
