Acute pancreatitis and type 2 diabetes mellitus: who is guilty?

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dc.contributor.authorKüçükler, Ferit Kerim
dc.contributor.authorŞimşek, Yasin
dc.contributor.authorBağlıcaklıoğlu, Murat
dc.contributor.authorAdalı Köroglu, Gupse
dc.contributor.authorGüler, Serdar
dc.date.accessioned2019-10-31T06:47:42Z
dc.date.available2019-10-31T06:47:42Z
dc.date.issued2015en_US
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractMany factors play a role in the etiology of acute pancreatitis and its pathogenesis is not fully understood. Dipeptidyl peptidase 4 (DPP-4) inhibitors are a new group of agents for the treatment of Diabetes Mellitus (DM). There are some controversies about specific adverse events such as pancreatitis and hypersensitivity reactions. A 50-year-old morbid obese woman presented with upper abdomen pain after the eating food, nausea and vomiting. She was diagnosed with type 2 diabetes mellitus 7 years ago. Vildagliptin had been added to her treatment six months ago. Abdominal examination revealed epigastric tenderness with guarding. Laboratory data revealed elevated pancreatic enzymes. Abdominal computed tomography (CT) showed features of pancreatitis. Vildagliptin was stopped and patient's symptoms had diminished in parallel with normalization of pancreatic enzymes; and at the 5th day patient was discharged with healthy condition. She was free of symptoms and all laboratory data were normal at the 30th day after discharge. It is important to keep in mind that diabetic patients have an increased risk of pancreatitis which may be related to obesity, hyperlipidemia and/or drugs.
dc.identifier.citationKucukler, F. K., Simsek, Y., Baglicaklioglu, M., Adali, G., Guler, S. (2015). Acute pancreatitis and type 2 diabetes mellitus: who is guilty?. The European Research Journal, 1(2), 74-77.
dc.identifier.doi10.18621/eurj.2015.1.2.74
dc.identifier.endpage77en_US
dc.identifier.issn2149-3189
dc.identifier.issue2en_US
dc.identifier.startpage74en_US
dc.identifier.urihttps://doi.org/10.18621/eurj.2015.1.2.74
dc.identifier.urihttps://hdl.handle.net/11491/4783
dc.identifier.volume1en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofThe European Research Journal
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDiabetes Mellitusen_US
dc.subjectAcute Pancreatitisen_US
dc.subjectDipeptidyl Peptidase 4 Inhibitorsen_US
dc.subjectMorbid Obesityen_US
dc.titleAcute pancreatitis and type 2 diabetes mellitus: who is guilty?
dc.typeArticle

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