Are there any causes for increased thyroid volume in women with prolactinoma?

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dc.contributor.authorAyçiçek Doğan, Berçem
dc.contributor.authorTaşçı, Tuğba
dc.contributor.authorArduç, Ayşe
dc.contributor.authorTuna, Mazhar Müslüm
dc.contributor.authorBerker, Dilek
dc.contributor.authorGüler, Serdar
dc.date.accessioned2019-05-10T09:38:47Z
dc.date.available2019-05-10T09:38:47Z
dc.date.issued2015
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractPurpose: The aim of this study was to evaluate thyroid volume in women with prolactinoma and investigate the relationship between anabolic hormones [insulin, insulin like growth factor (IGF-1), estrogen] and thyroid volume in the patients. Material-method: Sixty-three euthyroid women with prolactinoma and 60 healthy euthyroid women were included. Serum prolactin (PRL), thyroid-stimulating hormone (TSH), thyroxine (free T4), free tri-iodothyronine (free T3), insulin resistance (IR) which was estimated by the homeostasis model assessment, thyroidal microsome (anti-TPO), antithyroglobulin antibodies (TgAb), estradiol (E2), and insulin like growth factor (IGF-1) were evaluated, and thyroid volume was calculated by B-mode doppler USG. Results: The mean thyroid volume was significantly higher in women with prolactinoma (82.5 ± 15.1 mL) than in healthy women (76 ± 15.1 mL)(P = 0.014), but no correlation was found between thyroid volume and serum PRL levels (P = 0.967). There were also no differences between thyroid volume, anabolic hormones (E2, IGF-1), and insulin resistance in women with prolactinoma (P = 0.776, P = 0.786, P = 0.647, respectively). Conclusions: Our study did not show an association between anabolic hormones and increased thyroid volume in women with prolactinoma. © 2015 Elsevier Masson SAS.
dc.identifier.citationDoğan, B.A., Taşcı, T., Arduç, A., Tuna, M.M., Berker, D.S., Güler, S. (2015). Are there any causes for increased thyroid volume in women with prolactinoma? Annales d'endocrinologie, 76(5), 595-600 .
dc.identifier.doi10.1016/j.ando.2014.12.003
dc.identifier.endpage600en_US
dc.identifier.issn0003-4266
dc.identifier.issue5en_US
dc.identifier.scopusqualityQ2
dc.identifier.startpage595en_US
dc.identifier.urihttps://doi.org/10.1016/j.ando.2014.12.003
dc.identifier.urihttps://hdl.handle.net/11491/475
dc.identifier.volume76en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier Masson SAS
dc.relation.ispartofAnnales d'Endocrinologie
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAnabolic Hormonesen_US
dc.subjectProlactinomaen_US
dc.subjectThyroid Volumeen_US
dc.titleAre there any causes for increased thyroid volume in women with prolactinoma?
dc.typeArticle

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