Relationship between peritoneal permeability withinflammation and subclinical atherosclerosis inperitoneal dialysis patients
Yükleniyor...
Dosyalar
Tarih
2018
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
İnönü Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aim: High permeability in peritoneal dialysis (PD) is reported to be associated with increased mortality. Cardiovascular disease is the most important cause of morbidity and mortality in patients with end-stage renal disease. The inflammation is thought to take part in development of atherosclerosis. The aim of this study is to investigate the relation of peritoneal permeability type with carotid intima media thickness (CIMT) in PD patients. Material and Methods: Based on the standard peritoneal equilibration test, 56 PD patients (28 male) were divided in two transporter groups: low (low+low average) and high (high+high average) permeability. C-reactive protein (CRP) measured as a marker of inflammation and CIMT was evaluated by high-resolution B-mode ultrasonography. Results: Twenty one patients were low and 35 of them were high peritoneal transporters. Mean CRP level was significantly higher in the high permeability group (HPG) (1.62±1.7 vs 0.84±1 mg/dL; p=0.006). CIMT was higher in the HPG but this difference did not reach statistical significance (0.810±0.160 vs 0.740±0.160 mm; p=0.16). Conclusions: CRP, an indicator of inflammation, was found to be higher in the HPG. CIMT also was found to be higher in HPG although it was not statistically significant. One of the causes of increased mortality rate in this group of patients may be explained by inflammation and atherosclerosis.
Açıklama
research
Anahtar Kelimeler
Atherosclerosis, Inflammation, Peritoneal Dialysis, Peritoneal Permeability
Kaynak
Turgut Özal Tıp Merkezi Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
25
Sayı
1
Künye
Yayar, Ö., Eser, B., Bozkurt, A. (2018). Relationship between peritoneal permeability withinflammation and subclinical atherosclerosis inperitoneal dialysis patients. Turgut Özal Tıp Merkezi Dergisi, 25(1), 45-50.
