Predicting lympho-vascular space invasion in endometrial cancers with mucinous carcinomatous components
Yükleniyor...
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Asian Pacific Organization for Cancer Prevention
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: To determine the predictors of lympho-vascular space invasion (LVSI) in endometrial cancers which contain mucinous carcinomatous histology. Materials and Methods: Clinical and histopathological data of endometrial carcinomas with a mucinous carcinomatous component diagnosed between January 2007 and January 2014 at the Gynecologic Oncology Department of Zekai Tahir Burak Women's Health Education and Research Hospital were reviewed retrospectively. Results: Twelve patients (25.5%) were positive for LVSI and 35 (74.5%) patients were negative. Patients with LVSI were mostly staged higher than 1A. Mean age, BMI and parity were not significantly different between patient groups. Larger tumor diameter (?2cm) (p=0.04) and elevated Ca125 and Ca-19.9 (p=0.01) levels were significant for predicting LVSI. We also found >1/2 myometrial invasion (p<0.001), cervical stromal involvement (p=0.002) and higher grade (2-3) (p=0.001) significant for predicting LVSI. In multivariate analysis we found only grade significant for predicting LVSI. Conclusions: Especially grade of tumor is a crucial factor for determining LVSI in endometrial cancers with mucinous carcinomatous components.
Açıklama
Anahtar Kelimeler
Carcinoma, Endometrial, Grade, LVSI, Mucinous
Kaynak
Asian Pacific Journal of Cancer Prevention
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
16
Sayı
10
Künye
Selçuk, İ., Çetinkaya, N., Fırat Cuylan, Z., Özdal, B., Bayramoğlu, H., Güngör, T. (2015). Predicting lympho-vascular space invasion in endometrial cancers with mucinous carcinomatous components. Asian Pacific Journal of Cancer Prevention, 16(10), 4247-4250.
