Predicting lympho-vascular space invasion in endometrial cancers with mucinous carcinomatous components

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dc.contributor.authorSelçuk, İlker
dc.contributor.authorÇetinkaya, Nilüfer
dc.contributor.authorFırat Cuylan, Zeliha
dc.contributor.authorÖzdal, Bülent
dc.contributor.authorBayramoğlu, Hatice
dc.contributor.authorGüngör, Tayfun
dc.date.accessioned2019-05-13T09:04:04Z
dc.date.available2019-05-13T09:04:04Z
dc.date.issued2015
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractObjective: To determine the predictors of lympho-vascular space invasion (LVSI) in endometrial cancers which contain mucinous carcinomatous histology. Materials and Methods: Clinical and histopathological data of endometrial carcinomas with a mucinous carcinomatous component diagnosed between January 2007 and January 2014 at the Gynecologic Oncology Department of Zekai Tahir Burak Women's Health Education and Research Hospital were reviewed retrospectively. Results: Twelve patients (25.5%) were positive for LVSI and 35 (74.5%) patients were negative. Patients with LVSI were mostly staged higher than 1A. Mean age, BMI and parity were not significantly different between patient groups. Larger tumor diameter (?2cm) (p=0.04) and elevated Ca125 and Ca-19.9 (p=0.01) levels were significant for predicting LVSI. We also found >1/2 myometrial invasion (p<0.001), cervical stromal involvement (p=0.002) and higher grade (2-3) (p=0.001) significant for predicting LVSI. In multivariate analysis we found only grade significant for predicting LVSI. Conclusions: Especially grade of tumor is a crucial factor for determining LVSI in endometrial cancers with mucinous carcinomatous components.
dc.identifier.citationSelçuk, İ., Çetinkaya, N., Fırat Cuylan, Z., Özdal, B., Bayramoğlu, H., Güngör, T. (2015). Predicting lympho-vascular space invasion in endometrial cancers with mucinous carcinomatous components. Asian Pacific Journal of Cancer Prevention, 16(10), 4247-4250.
dc.identifier.doi10.7314/APJCP.2015.16.10.4247
dc.identifier.endpage4250en_US
dc.identifier.issn1513-7368
dc.identifier.issue10en_US
dc.identifier.scopusqualityQ3
dc.identifier.startpage4247en_US
dc.identifier.urihttps://doi.org/10.7314/APJCP.2015.16.10.4247
dc.identifier.urihttps://hdl.handle.net/11491/1584
dc.identifier.volume16en_US
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherAsian Pacific Organization for Cancer Prevention
dc.relation.ispartofAsian Pacific Journal of Cancer Prevention
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCarcinomaen_US
dc.subjectEndometrialen_US
dc.subjectGradeen_US
dc.subjectLVSIen_US
dc.subjectMucinousen_US
dc.titlePredicting lympho-vascular space invasion in endometrial cancers with mucinous carcinomatous components
dc.typeArticle

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