Negative life events have detrimental effects on in-vitro fertlization outcome

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dc.authorid0000-0002-8361-7908
dc.authorid0000-0002-0848-9731
dc.contributor.authorYılmaz, Nafiye
dc.contributor.authorKahyaoğlu, İnci
dc.contributor.authorİnal, Hasan Ali
dc.contributor.authorGörkem, Ümit
dc.contributor.authorDevran, Aysun
dc.contributor.authorMollamahmutoğlu, Leyla
dc.date.accessioned2019-05-13T09:03:56Z
dc.date.available2019-05-13T09:03:56Z
dc.date.issued2015
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractThe aim of this study was to investigate the effect of negative life events on in-vitro-fertilization (IVF) outcome. Depression and negative life events were measured using Beck Depression Inventory (BDI) and List of Recent Events in 83 women attending the IVF clinic of a tertiary research and education hospital with the diagnosis of unexplained infertility between January 2013 and August 2013. Demographic features, stimulation parameters, depression scores, and negative life events of pregnant and non-pregnant participants were compared and the relation between negative life events, depression scores, and IVF outcome was investigated. Women who did not achieve a pregnancy experienced more negative life events than women who became pregnant (77.2% vs. 23.1%) (p > 0.001). The number of patients with moderate-to-severe depression (BDI scores > 16) was higher in the non-pregnant group than pregnant group (49.1% vs. 26.9%), however the difference was not statistically significant (p = 0.057). Clinical pregnancy showed a significant moderate negative correlation with the number of negative life events (r =-0.513, p = 0.001), but the correlation between clinical pregnancy and BDI scores was not statistically significant (r =-0.209, p = 0.059). Stressful life events have a negative influence on the quality of life, which eventually affects in IVF outcome, possibly through maladaptive lifestyle behavior. © 2015 The British Fertility Society.
dc.identifier.citationYilmaz, N., Kahyaoglu, İ., İnal, H. A., Görkem, Ü., Devran, A., & Mollamahmutoglu, L. (2015). Negative life events have detrimental effects on in-vitro fertlization outcome. Human Fertility, 18(3), 220-224.
dc.identifier.doi10.3109/14647273.2015.1022607
dc.identifier.endpage224en_US
dc.identifier.issn1464-7273
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ2
dc.identifier.startpage220en_US
dc.identifier.urihttps://doi.org/10.3109/14647273.2015.1022607
dc.identifier.urihttps://hdl.handle.net/11491/1563
dc.identifier.volume18en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherTaylor and Francis Ltd
dc.relation.ispartofHuman Fertility
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectDepressionen_US
dc.subjectIVF Outcomeen_US
dc.subjectNegative Life Eventsen_US
dc.subjectIn-Vitro Fertilizationen_US
dc.titleNegative life events have detrimental effects on in-vitro fertlization outcome
dc.typeArticle

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