Effects of potentilla fulgens on tuba uterina in ovariectomized rats

Yükleniyor...
Küçük Resim

Tarih

2016

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Universidad de la Frontera

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

A total of 32 Wistar rats were divided into four equal groups: (I) sham, (II) ischemia, (III) reperfusion and (IV) Potentilla fulgens. In groups I and II, ovary torsion was not performed and no drug was administered. In group III, 1 h of ischemia and 2 h of reperfusion were performed and no drug was given. Group IV received 400 mg/kg/day Potentilla fulgens intraperitoneally 5 days before Ischemia-reperfusion. All the parameters were observed to be significantly decreased (P<0.05) in all the experimental groups compared to the control group. In the sections of the ischemia-reperfusion group, degeneration of epithelium, dilation of blood vessels were observed. Potentilla fulgens administration reduced the morphological changes by induced I/R; in particular, infiltration, hemorrhage and vascular dilatation were decreased. Potentilla fulgens application during torsion, it plays an important role in maintaining the epithelial structure with E-cadherin expression. We suggest that PECAM-1(CD31) are a regulator of the microvascular response of the tubal mucosa. © 2016, Universidad de la Frontera. All rights reserved.

Açıklama

Anahtar Kelimeler

Ischemia-Reperfusion, Potentilla Fulgens, Rat, Tuba Uterina

Kaynak

International Journal of Morphology

WoS Q Değeri

N/A

Scopus Q Değeri

Q3

Cilt

34

Sayı

2

Künye

Acar, Z., Değer, U., Görkem, Ü., Toğrul, C., Deveci, E., Kaya, S., Ekinci, A. (2016).Effects of potentilla fulgens on tuba uterina in ovariectomized rats. International Journal of Morphology, 34(2), 460-464.