Synthesis of a bipyridine-derived achiral thiourea trifluoromethanesulfonic acid salt and its application as an additive in organocatalytic asymmetric reactions
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Tarih
2013
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The host-guest complex of a proline-thiourea bipyridine trifluoromethanesulfonic acid salt can catalyze organocatalytic asymmetric reactions such as aldol, Michael, and Mannich in polar protic medium with high stereoselectivities. The privileged bipyridine backbone and the thiourea motif are essential to the activity and enantioselectivity through hydrogen bonding interactions. © 2013 Elsevier Ltd. All rights reserved.
Açıklama
Anahtar Kelimeler
Asymmetric Aldol Reaction, Asymmetric Mannich Reaction, Enantioselective Michael Reaction, Host-Guest Complex, Proline-Thiourea Interaction
Kaynak
Tetrahedron Letters
WoS Q Değeri
N/A
Scopus Q Değeri
Q3
Cilt
54
Sayı
42
Künye
Demir, A. S., & Basceken, S. (2013). Synthesis of a bipyridine-derived achiral thiourea trifluoromethanesulfonic acid salt and its application as an additive in organocatalytic asymmetric reactions. Tetrahedron Letters, 54(42), 5677-5681.
