Incidence of renal carcinoma in non-functioning kidney due to renal pelvic stone disease

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dc.authoridIMAMOGLU, MUHAMMET ABDURRAHIM / 0000-0003-3848-7312
dc.contributor.authorZengin, Kursad
dc.contributor.authorTanik, Serhat
dc.contributor.authorSener, Nevzat Can
dc.contributor.authorAlbayrak, Sebahattin
dc.contributor.authorEkici, Musa
dc.contributor.authorBozkurt, Ibrahim Halil
dc.contributor.authorImamoglu, Muhammed Abdurrahim
dc.date.accessioned2021-11-01T14:58:16Z
dc.date.available2021-11-01T14:58:16Z
dc.date.issued2015
dc.department[Belirlenecek]
dc.description.abstractThe objective of this study was to report our pathological findings in nephrectomy specimens from patients treated for non-functioning hydronephrotic kidney due to renal pelvic stone disease. A total of 97 patients who underwent nephrectomy for non-functioning hydronephrotic kidneys between January, 2011 and June, 2014 were retrospectively reviewed. A non-functioning kidney was defined as one having paper-thin parenchyma on urinary ultrasound or computed tomography, exhibiting no contrast visualization in the collecting duct system on intravenous urography and having a split renal function of <10% on nuclear renal function studies. Following pathological evaluation, 9 patients were diagnosed with xanthogranulomatous pyelonephritis, 9 with malignant tumors and 79 with chronic pyelonephritis. Of the patients with chronic pyelonephritis, 2 also had renal adenomas. The malignant tumors included 3 transitional cell carcinomas (TCC), 2 squamous cell carcinomas (SCC), 3 renal cell carcinomas (RCC) (1 sarcomatoid, 1 papillary and 1 clear cell RCC), whereas 1 patient had concurrent RCC and TCC. In conclusion, non-functioning kidneys, particularly those with kidney stones, should be managed as possible malignancies, due to the higher incidence of malignant tumors in such patients compared with the normal population.
dc.identifier.doi10.3892/mco.2015.550
dc.identifier.endpage943en_US
dc.identifier.issn2049-9450
dc.identifier.issn2049-9469
dc.identifier.issue4en_US
dc.identifier.pmid26171211
dc.identifier.startpage941en_US
dc.identifier.urihttps://doi.org/10.3892/mco.2015.550
dc.identifier.urihttps://hdl.handle.net/11491/6559
dc.identifier.volume3en_US
dc.identifier.wosWOS:000453156700039
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.institutionauthor[Belirlenecek]
dc.language.isoen
dc.publisherSpandidos Publ Ltd
dc.relation.ispartofMolecular And Clinical Oncology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectnon-functioning kidneyen_US
dc.subjectrenal carcinomaen_US
dc.subjectrenal stoneen_US
dc.titleIncidence of renal carcinoma in non-functioning kidney due to renal pelvic stone disease
dc.typeArticle

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