Synthesis, characterization, powder X-ray diffraction analysis, thermal stability, antioxidant properties and enzyme inhibitions of M(II)-Schiff base ligand complexes

Basit Öğe Kaydı
dc.authoridMantarci, Asim / 0000-0001-8369-3559
dc.authoridTuran, Nevin / 0000-0001-6740-6812
dc.authoridBULDURUN, Kenan / 0000-0002-2462-7006
dc.authoridBursal, Ercan / 0000-0001-7289-4507
dc.authoridGulcin, ilhami / 0000-0001-5993-1668
dc.authorwosidMantarci, Asim / R-7945-2016
dc.authorwosidGulcin, ilhami / F-1428-2014
dc.contributor.authorBuldurun, Kenan
dc.contributor.authorTuran, Nevin
dc.contributor.authorBursal, Ercan
dc.contributor.authorAras, Abdulmelik
dc.contributor.authorMantarci, Asim
dc.contributor.authorColak, Naki
dc.contributor.authorGulcin, Ilhami
dc.date.accessioned2021-11-01T15:06:01Z
dc.date.available2021-11-01T15:06:01Z
dc.date.issued2021
dc.department[Belirlenecek]
dc.description.abstractThe Schiff base ligand ((E)-6-methyl-2-(2,3,4-trimethoxybenzylideneamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbonitrile) and its cobalt(II) and palladium(II) complexes were successfully prepared. The structure of the compounds was elucidated by various techniques (NMR, FT-IR, powder X-ray diffraction, microanalysis, TGA, magnetic susceptibility, mass spectrometry). The Pd(II) complex showed a square planar geometry and the Co(II) complex had an octahedral geometry. ABTS (2,2-azino-bis 3-ethylbenzothiazloine-6-sulphonic acid), DPPH (1,1-diphenyl-2-picrylhydrazyl), FRAP (ferric-reducing antioxidant power) and CUPRAC (cupric reducing antioxidant capacity)in vitromethods were applied to identify the antioxidant features of the synthesized compounds. In addition, glutathione S-transferase and acetyl/butyryl cholinesterase enzymes were examined for possible inhibition capacities of the complexes. According to the enzyme activity measurements, Ru(II) complex inhibited both GST and BChE enzymes, while Fe(II) complex inhibited only AChE enzyme. Furthermore, the antioxidant activities and enzyme inhibitions of the previously synthesized Fe(II) and Ru(II) complexes of the same ligand were examined to make a comparison of the metal complexes. Communicated by Ramaswamy H. Sarma
dc.identifier.doi10.1080/07391102.2020.1802340
dc.identifier.endpage6487en_US
dc.identifier.issn0739-1102
dc.identifier.issn1538-0254
dc.identifier.issue17en_US
dc.identifier.pmid32752945
dc.identifier.scopus2-s2.0-85089022891
dc.identifier.scopusqualityQ1
dc.identifier.startpage6480en_US
dc.identifier.urihttps://doi.org/10.1080/07391102.2020.1802340
dc.identifier.urihttps://hdl.handle.net/11491/7470
dc.identifier.volume39en_US
dc.identifier.wosWOS:000555652500001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthor[Belirlenecek]
dc.language.isoen
dc.publisherTaylor & Francis Inc
dc.relation.ispartofJournal Of Biomolecular Structure & Dynamics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectMetal complexen_US
dc.subjectSchiff baseen_US
dc.subjectspectroscopic techniquesen_US
dc.subjectantioxidant activityen_US
dc.subjectenzyme inhibitionen_US
dc.titleSynthesis, characterization, powder X-ray diffraction analysis, thermal stability, antioxidant properties and enzyme inhibitions of M(II)-Schiff base ligand complexes
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu