Self-assembly of an organocatalyst for the enantioselective synthesis of Michael adducts and ?-aminoxy alcohols in a nonpolar medium
| dc.authorid | 0000-0002-6311-1918 | |
| dc.contributor.author | Basçeken, Sinan | |
| dc.date.accessioned | 2019-05-13T08:58:23Z | |
| dc.date.available | 2019-05-13T08:58:23Z | |
| dc.date.issued | 2013 | |
| dc.department | Hitit Üniversitesi, Fen Edebiyat Fakültesi, Kimya Bölümü | |
| dc.description.abstract | A proline-thiourea host-guest complex is described as a self-assembled organocatalyst for the enantioselective Michael addition of aldehydes to nitroolefins and for the asymmetric ?-aminoxylation of both aldehydes and ketones. The Michael adducts were obtained in good yields of up to 80%, high diastereoselectivities of up to 5:95, and high enantiomeric excesses of up to 98%. The optically active aminoxy alcohols were synthesized in 60-85% yields with 94-99% enantiomeric excesses after reduction of the ?-oxidation products using NaBH4. © 2013 Elsevier Ltd. All rights reserved. | |
| dc.identifier.citation | Demir, A. S., Basçeken, S. (2013). Self-assembly of an organocatalyst for the enantioselective synthesis of Michael adducts and ?-aminoxy alcohols in a nonpolar medium. Tetrahedron: Asymmetry, 24(19), 1218-1224. | |
| dc.identifier.doi | 10.1016/j.tetasy.2013.08.008 | |
| dc.identifier.endpage | 1224 | en_US |
| dc.identifier.issn | 0957-4166 | |
| dc.identifier.issue | 19 | en_US |
| dc.identifier.scopusquality | N/A | |
| dc.identifier.startpage | 1218 | en_US |
| dc.identifier.uri | https://doi.org/10.1016/j.tetasy.2013.08.008 | |
| dc.identifier.uri | https://hdl.handle.net/11491/1127 | |
| dc.identifier.volume | 24 | en_US |
| dc.identifier.wosquality | N/A | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.language.iso | en | |
| dc.relation.ispartof | Tetrahedron Asymmetry | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.subject | [Belirlenecek] | en_US |
| dc.title | Self-assembly of an organocatalyst for the enantioselective synthesis of Michael adducts and ?-aminoxy alcohols in a nonpolar medium | |
| dc.type | Article |
