Spectrophotometric determination of acidity constants of some macrolides in acetonitrile-water binary mixtures

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Tarih

2010

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

The acidity constants of eight macrolides (erythromycin, roxithromycin, oleandomycin, azithromycin, josamycin, tylosin tartrate, tilmicosin and spiramycin) have been determined in acetonitrile-water binary mixtures (30%, 40% and 50% (v/v)) by spectrophotometric method. The pKa's available in literature determined by various methods are compiled in comparison with the value of this work. These results are expected to essentially facilitate the research on occurrence, fate and effects, analysis method development, and control of antibiotics in various treatment occurrences.

Açıklama

Anahtar Kelimeler

Acetonitrile-Water Mixtures, Acidity Constants, Macrolides, Spectroscopic Method

Kaynak

Acta Chimica Slovenica

WoS Q Değeri

N/A

Scopus Q Değeri

Q3

Cilt

57

Sayı

4

Künye

Şanlı, S., Şanlı, N., Alsancak, G. (2010). Spectrophotometric determination of acidity constants of some macrolides in acetonitrile-water binary mixtures. Acta Chimica Slovenica, 57(4), 980-987.