Autologous platelet-rich plasma in treatment of chronic venous leg ulcers: A prospective case series

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dc.authorid0000-0002-8782-7603
dc.contributor.authorYılmaz, Seyhan
dc.contributor.authorAksoy, Eray
dc.contributor.authorDoğancı, Suat
dc.contributor.authorYalçınkaya, Adnan
dc.contributor.authorDiken, Adem İlkay
dc.contributor.authorÇağlı, Kerim
dc.date.accessioned2019-05-13T09:07:01Z
dc.date.available2019-05-13T09:07:01Z
dc.date.issued2015
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractStudy: We report our results on a case series of 19 patients receiving platelet-rich plasma application in treatment of patients with chronic unhealing venous leg ulcers. Material and methods: There were 16 males and three females with a mean age of 38.55 ± 16.46 years. Planimetric size measurements were performed and pain was tested throughout the treatment period. Follow-up was made in seven-day periods. Patients received 5 ml of platelet-rich plasma for each 5 cm2 of the wound surface with half of the amount being injected 1–2 mm deep into the wound and the wound surface was covered with the remaining half. Results: Complete wound healing occurred in 18 of 19 patients (94.7%) within a mean of 4.82 ± 2.16 week. There were significant reductions in wound area among all consecutive measurements except for first week. A significant reduction in wound volume was apparent even in first week and sustained among consecutive measurements. Conclusion: Platelet-rich plasma seems effective in terms of promoting healing of venous leg ulcers. Improvement in wound depth was slightly more prominent than that in wound area, indicating a potential role of platelet-rich plasma especially in deep venous ulcers. © 2014, © The Author(s) 2014.
dc.identifier.citationYılmaz, S., Aksoy, E., Doğancı, S., Yalçınkaya, A., Diken, A. İ., Çağlı, K. (2015). Autologous platelet-rich plasma in treatment of chronic venous leg ulcers: A prospective case series. Vascular, 23(6), 580-585.
dc.identifier.doi10.1177/1708538114563824
dc.identifier.endpage585en_US
dc.identifier.issn1708-5381
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ2
dc.identifier.startpage580en_US
dc.identifier.urihttps://doi.org/10.1177/1708538114563824
dc.identifier.urihttps://hdl.handle.net/11491/1702
dc.identifier.volume23en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSAGE Publications Ltd
dc.relation.ispartofVascular
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectChronic Venous Insufficiencyen_US
dc.subjectPlatelet-Rich Plasmaen_US
dc.subjectWounden_US
dc.titleAutologous platelet-rich plasma in treatment of chronic venous leg ulcers: A prospective case series
dc.typeArticle

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