Comparison of pentraxin-3 and ischemia-modified albumin with troponin in early diagnosis of acute coronary syndrome

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dc.contributor.authorDemir, Muhammed Taha
dc.contributor.authorBaydın, Ahmet
dc.contributor.authorAmanvermez, Ramazan
dc.contributor.authorErenler, Ali Kemal
dc.contributor.authorGüzel, Murat
dc.contributor.authorYücel, Osman
dc.date.accessioned2019-05-10T09:38:48Z
dc.date.available2019-05-10T09:38:48Z
dc.date.issued2018
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractINTRODUCTION: In this study, our aim was to evaluate clinical utilities of Pentraxin 3 (PTX3) and Ischemiamodified Albumin (IMA) in diagnosis of acute coronary syndrome (ACS) and compare these two biomarkers with a conventional diagnostic marker, cardiac troponin I (cTnI). MATERIALS AND METHODS: Sixty adult patients with ACS diagnosis were involved into this prospective study. Addi tionally, 20 healthy subjects were determined as control group (Group IV). Patients were divided into 3 groups as follows: Patients with Acute Myocardial Infarction (STEMI Group, n=20, Group I), patients without ST elevation but with elevated cTnI levels (NSTEMI Group, n=20, Group II), and patients with unstable angina pectoris (USAP Group, n=20, Group III). Blood measurements were obtained for each marker at admission and in the 4th hour. RESULTS: Troponin level was significantly different between groups I and II at both admission and in the 4th hour. Additionally, PTX 3 level was significantly different at admission and 4th hour between groups II and III. CONCLUSION: This study revealed that cTnI is the most sensitive test in ACS diagnosis at the admission to Emergency Department. Our results also revealed that PTX 3 may be a useful diagnostic tool for ACS at admission, however, IMA alone cannot be used for diagnosis of ACS. Similarly, in the 4th hour, cTnI was found to be the most useful marker in ACS diagnosis, however, PTX 3 and IMA were found to be inadequate for diagnosis of ACS. © 2018, Comenius University.
dc.identifier.citationDemir, M. T., Baydin, A., Amanvermez, R., Erenler, A. K., Güzel, M., Yücel, O. (2018). Comparison of pentraxin-3 and ischemia-modified albumin with troponin in early diagnosis of acute coronary syndrome. Bratislavske lekarske listy, 119(8), 509-512.
dc.identifier.doi10.4149/BLL_2018_093
dc.identifier.endpage512en_US
dc.identifier.issn0006-9248
dc.identifier.issue8en_US
dc.identifier.scopusqualityQ2
dc.identifier.startpage509en_US
dc.identifier.urihttps://doi.org/10.4149/BLL_2018_093
dc.identifier.urihttps://hdl.handle.net/11491/483
dc.identifier.volume119en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherComenius University
dc.relation.ispartofBratislava Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAcute Coronary Syndromeen_US
dc.subjectCardiac Troponin ien_US
dc.subjectEmergency Departmenten_US
dc.subjectIschemia-Modified Albuminen_US
dc.subjectPentraxin-3en_US
dc.titleComparison of pentraxin-3 and ischemia-modified albumin with troponin in early diagnosis of acute coronary syndrome
dc.typeArticle

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