Spectral analysis and biological activity assessment of silver doped hydroxyapatite

Basit Öğe Kaydı
dc.authorscopusid57202858239
dc.authorscopusid57188658010
dc.authorscopusid55440676700
dc.authorscopusid26634035600
dc.authorscopusid28368085800
dc.authorscopusid8920503400
dc.authorscopusid6603276101
dc.contributor.authorErdem, Ümit
dc.contributor.authorMoran Bozer, Büşra
dc.contributor.authorTürköz, Mustafa B.
dc.contributor.authorMetin, Ayşegül Ülkü
dc.contributor.authorYıldırım, Gürcan
dc.contributor.authorTürk, Mustafa
dc.contributor.authorNezir, Saffet
dc.date.accessioned2021-11-01T14:51:34Z
dc.date.available2021-11-01T14:51:34Z
dc.date.issued2021
dc.departmentRektörlük
dc.description.abstractIn this study, the hydroxyapatite biomaterials are produced by the precipitation method and the role of silver doping within the different molar ratios of 2.0, 5.0, and 10.0% are investigated with some fundamental analysis, including powder XRD, SEM, EDS, FTIR, Raman, and material densities. In vitro biocompatibility assessment is conducted with cytotoxicity and agar diffusion tests. Moreover, genotoxicity tests determine whether the biomaterials produced cause the mutations or not. In addition, a hemolytic effect test examines the variation of hemolytic behavior of compounds. Also, the cell migration experiments inspect the influence of silver ion levels in biomaterials on many biological processes. The experimental results reveal that the honeycomb-patterned morphological structures are obtained for all the products. FTIR and Raman analyses reveal that the dramatic changes in the characteristic functional group peaks are obtained with the increment in the amount of silver ions. The experimental parts related to the biocompatibility assessment of the study show that there seems to be deterioration in biocompatibility as the silver ion-doping level increases in the system. To sum up, the ideal doping value for bone tissue engineering applications is found to be 2%. © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of The Korean Ceramic Society and The Ceramic Society of Japan.
dc.identifier.citationErdem, U., Bozer, B. M., Turkoz, M. B., Metin, A. U., Yıldırım, G., Turk, M., & Nezir, S. (2021). Spectral analysis and biological activity assessment of silver doped hydroxyapatite. Journal of Asian Ceramic Societies, 1-22.
dc.identifier.doi10.1080/21870764.2021.1989749
dc.identifier.issn2187-0764
dc.identifier.scopus2-s2.0-85117349655
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1080/21870764.2021.1989749
dc.identifier.urihttps://hdl.handle.net/11491/6184
dc.identifier.wosWOS:000708270000001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorMoran Bozer, Büşra
dc.language.isoen
dc.publisherTaylor and Francis Ltd.
dc.relation.ispartofJournal of Asian Ceramic Societies
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBiocompabilityen_US
dc.subjectCell Migrationen_US
dc.subjectHydroxyapatiteen_US
dc.subjectSilver Dopingen_US
dc.titleSpectral analysis and biological activity assessment of silver doped hydroxyapatite
dc.typeArticle

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu