The Effect of Exercise on Serum Homocysteine, Adma, Neopterin and Oxidative Stress Levels in Young Male Athletes

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dc.authoridCan, Sema / 0000-0003-1931-2226
dc.authorwosidCan, Sema / ABE-9758-2020
dc.authorwosidDemirkan, Erkan / AAO-5672-2021
dc.authorwosidCan, Sema / AAN-2932-2021
dc.contributor.authorCan, Sema
dc.contributor.authorDemirkan, Erkan
dc.contributor.authorAvcı, Emre
dc.date.accessioned2021-11-01T15:01:48Z
dc.date.available2021-11-01T15:01:48Z
dc.date.issued2018
dc.departmentHitit Üniversitesi, Spor Bilimleri Fakültesi, Antrenörlük Eğitimi Bölümü
dc.departmentHitit Üniversitesi, Fen Edebiyat Fakültesi, Moleküler Biyoloji ve Genetik Bölümü
dc.description.abstractElevated homocysteine (HCY), asymmetric dimethylarginine (ADMA), Neopterin (NP) and oxidative stress have been established as risk factors for vascular disease and coronary artery disease. The purpose of the study was (a) to assess the HCY, ADMA, NP, malondialdehyde (MDA) and glutathione (GSH) levels and (b) to determine the relationship between these parameters in wrestlers, track and field athletes, and non-athletes. 35 subjects in total, comprising of 15 wrestlers ((x) over bar = 17.6 +/- 2.3 years), 10 track and field athletes ((x) over bar = 16.6 +/- 2.2 years) and 10 non-athletes((x) over bar = 17.2 +/- 0.8 years) voluntarily participated in the study. The HCY, ADMA, NP, MDA, GSH levels as in subjects' blood was performed through the antecubital vein in the morning while in the pre-prandial state. There was a significant difference in ADMA, MDA, GSH concentrations between in track and field athletes and wrestlers. There was a significant difference in HCY, NP concentrations between wrestlers and non-athletes. There was a significant difference in HCY, MDA concentrations between track and field athletes and non-athletes (p< 0.05). The HCY and NP showed high level correlation in all groups (track and field athletes; r = .952; wrestlers; r = .886; non-athletes; r = .900; p< 0.01). The GSH and NP showed high level negative correlation in non-athletes (r = - .900; p< 0.01). According to the results of HCY, ADMA, NP, MDA, the lowest level was found in athletes and the highest appeared in the non-athletes. In conclusion, we think that regular training may have positive effects on cardiovascular and anti antioxidant level.
dc.identifier.citationCan, S., Demirkan, E., & Avcı, E. (2018). The effect of exercise on serum Homocysteine, Adma, Neopterin and oxidative stress levels in Young male athletes. International Journal of Applied Exercise Physiology, 7(4), 17-29.
dc.identifier.doi10.30472/ijaep.v7i4.290
dc.identifier.endpage29en_US
dc.identifier.issn2322-3537
dc.identifier.issue4en_US
dc.identifier.startpage17en_US
dc.identifier.urihttps://doi.org/10.30472/ijaep.v7i4.290
dc.identifier.urihttps://hdl.handle.net/11491/6682
dc.identifier.volume7en_US
dc.identifier.wosWOS:000451875300003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.institutionauthorCan, Sema
dc.institutionauthorDemirkan, Erkan
dc.institutionauthorAvcı, Emre
dc.language.isoen
dc.publisherInt Journal Applied Exercise Physiology
dc.relation.ispartofInternational Journal Of Applied Exercise Physiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAsymmetric dimethylarginineen_US
dc.subjectGlutathioneen_US
dc.subjectNeopterinen_US
dc.subjectHomocysteineen_US
dc.subjectMalondialdehydeen_US
dc.titleThe Effect of Exercise on Serum Homocysteine, Adma, Neopterin and Oxidative Stress Levels in Young Male Athletes
dc.typeArticle

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