Antimicrobial activities, absorption characteristics and tautomeric structures of o,o’-hydroxyazo dyes containing an acryloyloxy group and their chromium complexes
Yükleniyor...
Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Hacettepe University
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
E-1-((2-hydroxy-5-methylphenyl)diazenyl)naphthalene-2,7-diol’ün ve akrilat türevlerinin ve onların krom komplekslerinin farklı çözücüler, pH ve sıcaklıklardaki UV-VIS davranışları tespit edildi. Çözücü içinde boyalar azo ve hidroazo tautomeric dengede bulundu. Aynı zamanda o,o’-dihydroksi azo boyaları ve krom komplekleri Enterococcus faecalis, Staphylococcus aureus, Pseudomonas aeroginosa, Escherichia coli ve Candida albicans antimikrobiyal aktivite açısından test edildi. Boya I genellikle tüm mikroorganizmalar üzerine etkili iken, II, III ve IV’ cü bileşikler P. aeroginosa ve E. coli üzerine daha fazla etkilidir. Boya I hem bakteriler hem de mayalar üzerinde antimikrobiyal etkiye sahip olduğu için, tekstilde lif boyaması ve biyomedikal çalışmalar gibi çeşitli uygulamalarda kullanımı uygun bulunmuştur. Bu boya önemli ölçüde yeni antifungal ilaçların geliştirilmesine yol açabilir.
The UV-VIS behavior of (E)-1-((2-hydroxy-5-methylphenyl)diazenyl)naphthalene-2,7-diol and the acrylate derivatives and their chromium complexes were determined in different solvents, pH and temperature. The dyes were found to exist in azo and hydrazone tautomeric equilibrium in solution. And also, the o,o’- dihydroxyazo dyes and chromium complexes were tested for antimicrobial activity against Enterococcus faecalis, Staphylococcus aureus, Pseudomonas aeroginosa, Escherichia coli and Candida albicans. Dye I generally affected all microorganisms, while compounds II, III and IV were more effective against P. aeroginosa and E. coli. Because dye I has an antimicrobial effect on both bacteria and fungus it finds good use in various applications such as textile fiber dyeing, and biomedical studies. Significantly, this dye could also lead to the development of new antifungal drugs.
The UV-VIS behavior of (E)-1-((2-hydroxy-5-methylphenyl)diazenyl)naphthalene-2,7-diol and the acrylate derivatives and their chromium complexes were determined in different solvents, pH and temperature. The dyes were found to exist in azo and hydrazone tautomeric equilibrium in solution. And also, the o,o’- dihydroxyazo dyes and chromium complexes were tested for antimicrobial activity against Enterococcus faecalis, Staphylococcus aureus, Pseudomonas aeroginosa, Escherichia coli and Candida albicans. Dye I generally affected all microorganisms, while compounds II, III and IV were more effective against P. aeroginosa and E. coli. Because dye I has an antimicrobial effect on both bacteria and fungus it finds good use in various applications such as textile fiber dyeing, and biomedical studies. Significantly, this dye could also lead to the development of new antifungal drugs.
Açıklama
research
Anahtar Kelimeler
O,o’-Dihydroxyazo, Antimicrobial Activity, Azo-ester Dyes, Chromium Complexes, Antimikrobiyal Aktivite, Azo-ester Boyaları, Krom Kompleksleri
Kaynak
Hacettepe Journal of Biology and Chemistry
WoS Q Değeri
Scopus Q Değeri
Cilt
40
Sayı
2
Künye
Alp Avcı, G., Özkınalı, S., Özlük, A., Avcı, E., Kocaokutgen, H. (2012). Antimicrobial activities, absorption characteristics and tautomeric structures of o, o’-hydroxyazo dyes containing an acryloyloxy group and their chromium complexes. Hacettepe Journal of Biology and Chemistry, 40(2), 119-126.
