The impact of follicular fluid adiponectin and ghrelin levels based on BMI on IVF outcomes in PCOS
[ X ]
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer International Publishing
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Purpose: This study aimed at evaluating the effects of polycystic ovary syndrome (PCOS) and body mass index (BMI) on follicular fluid (FF) adiponectin and ghrelin levels, and on in vitro fertilization outcomes in patients who underwent controlled ovarian hyperstimulation. Methods: This prospective cross-sectional study was performed with a total of 120 primary infertile women [group 1; non-PCOS = 60 (BMI <25 = 30, BMI ?25 = 30) and group 2; PCOS = 60 (BMI <25 = 30, BMI ?25 = 30)]. On the day of oocyte pickup, FF samples were collected. Results: The FF adiponectin levels were lower in the lean PCOS group than the lean non-PCOS group (p = 0.001), and these levels were lower in the overweight non-PCOS group compared to lean non-PCOS group (0.001). However, there was no difference in the FF ghrelin levels between the groups. Additionally, we could not find a relationship between clinical pregnancy and adiponectin and ghrelin levels. Conclusion: The FF adiponectin and ghrelin levels have no effects on clinical pregnancy in PCOS. Therefore, further studies are needed to elucidate this issue.
Açıklama
Anahtar Kelimeler
Adiponectin, ART, Ghrelin, IVF Outcomes, Polycystic Ovary Syndrome
Kaynak
Journal of Endocrinological Investigation
WoS Q Değeri
N/A
Scopus Q Değeri
Q1
Cilt
39
Sayı
4
Künye
Inal, H. A., Yilmaz, N., Gorkem, U., Oruc, A. S., & Timur, H. (2016). The impact of follicular fluid adiponectin and ghrelin levels based on BMI on IVF outcomes in PCOS. Journal of endocrinological investigation, 39(4), 431-437.
