The impact of follicular fluid adiponectin and ghrelin levels based on BMI on IVF outcomes in PCOS

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dc.authorid0000-0002-8361-7908
dc.authorid0000-0002-0848-9731
dc.contributor.authorİnal, Hasan Ali
dc.contributor.authorYılmaz, Nafiye
dc.contributor.authorGörkem, Ümit
dc.contributor.authorSargın Oruç, Ayla
dc.contributor.authorTimur, Hakan
dc.date.accessioned2019-05-13T08:57:30Z
dc.date.available2019-05-13T08:57:30Z
dc.date.issued2016
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractPurpose: This study aimed at evaluating the effects of polycystic ovary syndrome (PCOS) and body mass index (BMI) on follicular fluid (FF) adiponectin and ghrelin levels, and on in vitro fertilization outcomes in patients who underwent controlled ovarian hyperstimulation. Methods: This prospective cross-sectional study was performed with a total of 120 primary infertile women [group 1; non-PCOS = 60 (BMI <25 = 30, BMI ?25 = 30) and group 2; PCOS = 60 (BMI <25 = 30, BMI ?25 = 30)]. On the day of oocyte pickup, FF samples were collected. Results: The FF adiponectin levels were lower in the lean PCOS group than the lean non-PCOS group (p = 0.001), and these levels were lower in the overweight non-PCOS group compared to lean non-PCOS group (0.001). However, there was no difference in the FF ghrelin levels between the groups. Additionally, we could not find a relationship between clinical pregnancy and adiponectin and ghrelin levels. Conclusion: The FF adiponectin and ghrelin levels have no effects on clinical pregnancy in PCOS. Therefore, further studies are needed to elucidate this issue.
dc.identifier.citationInal, H. A., Yilmaz, N., Gorkem, U., Oruc, A. S., & Timur, H. (2016). The impact of follicular fluid adiponectin and ghrelin levels based on BMI on IVF outcomes in PCOS. Journal of endocrinological investigation, 39(4), 431-437.
dc.identifier.doi10.1007/s40618-015-0392-6
dc.identifier.endpage437en_US
dc.identifier.issn0391-4097
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ1
dc.identifier.startpage431en_US
dc.identifier.urihttps://doi.org/10.1007/s40618-015-0392-6
dc.identifier.urihttps://hdl.handle.net/11491/942
dc.identifier.volume39en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherSpringer International Publishing
dc.relation.ispartofJournal of Endocrinological Investigation
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAdiponectinen_US
dc.subjectARTen_US
dc.subjectGhrelinen_US
dc.subjectIVF Outcomesen_US
dc.subjectPolycystic Ovary Syndromeen_US
dc.titleThe impact of follicular fluid adiponectin and ghrelin levels based on BMI on IVF outcomes in PCOS
dc.typeArticle

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