Outcome of the Respiratory Syncytial Virus related acute lower respiratory tract infection among hospitalized newborns: A prospective multicenter study

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dc.contributor.authorAlan, Serdar
dc.contributor.authorErdeve, Ömer
dc.contributor.authorÇakır, Ufuk
dc.contributor.authorAkduman, Hasan
dc.contributor.authorZenciroğlu, Ayşegül
dc.contributor.authorAkçakuş, Mustafa
dc.contributor.authorTunç, Turan
dc.contributor.authorGökmen, Zeynel
dc.date.accessioned2019-05-13T09:04:01Z
dc.date.available2019-05-13T09:04:01Z
dc.date.issued2016
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractAim: To determine the incidence and outcomes of respiratory syncytial virus (RSV)-related acute lower respiratory tract infection (ALRI) including morbidity, nosocomial infection and mortality among newborn infants who were admitted to the neonatal intensive care units (NICUs).Methods: A multicenter, prospective study was conducted in newborns who were hospitalized with community acquired or nosocomial RSV infection in 44 NICUs throughout Turkey. Newborns with ALRI were screened for RSV infection by Respi-Strip®-test. Main outcome measures were the incidence of RSV-associated admissions in the NICUs and morbidity, mortality and epidemics results related to these admissions.Findings: The incidence of RSV infection was 1.24% (n: 250) and RSV infection constituted 19.6% of all ALRI hospitalizations, 226 newborns (90.4%) had community-acquired whereas 24 (9.6%) patients had nosocomial RSV infection in the NICUs. Of the 250 newborns, 171 (68.4%) were full-term infants, 183 (73.2%) had a BW >2500 g. RSV-related mortality rate was 1.2%. Four NICUs reported seven outbreaks on different months, which could be eliminated by palivizumab prophylaxis in one NICU.Conclusion: RSV-associated ALRI both in preterm and term infants accounts an important percent of hospitalizations in the season, and may threat other high-risk patients in the NICU. © 2015 Taylor & Francis.
dc.identifier.citationAlan, S., Erdeve, O., Cakir, U., Akduman, H., Zenciroglu, A., Akcakus, M., ... & Arsan, S. (2016). Outcome of the respiratory syncytial virus related acute lower respiratory tract infection among hospitalized newborns: a prospective multicenter study. The Journal of Maternal-Fetal & Neonatal Medicine, 29(13), 2186-2193.
dc.identifier.doi10.3109/14767058.2015.1079614
dc.identifier.endpage2193en_US
dc.identifier.issn1476-7058
dc.identifier.issue13en_US
dc.identifier.scopusqualityQ1
dc.identifier.startpage2186en_US
dc.identifier.urihttps://doi.org/10.3109/14767058.2015.1079614
dc.identifier.urihttps://hdl.handle.net/11491/1576
dc.identifier.volume29en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherTaylor and Francis Ltd
dc.relation.ispartofJournal of Maternal-Fetal and Neonatal Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectNeonatal Intensive Care Uniten_US
dc.subjectNewbornen_US
dc.subjectNosocomialen_US
dc.subjectOutbreaken_US
dc.subjectRespiratory Syncytial Virusen_US
dc.titleOutcome of the Respiratory Syncytial Virus related acute lower respiratory tract infection among hospitalized newborns: A prospective multicenter study
dc.typeArticle

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