Subclinical Cardiovascular Risk Factors in Chronic Kidney Disease: Abnormal Heart Rate Recovery

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dc.contributor.authorTurgut, Didem
dc.contributor.authorYenigün, Ezgi Coşkun
dc.contributor.authorKundi, Harun
dc.contributor.authorÖzyakar, Nihal
dc.contributor.authorDede, Fatih
dc.date.accessioned2021-11-01T18:14:58Z
dc.date.available2021-11-01T18:14:58Z
dc.date.issued2020
dc.department[Belirlenecek]
dc.description.abstractObjective: Chronic kidney disease (CKD) is associated with increased mortality and high cardiovascular (CV) risk. Slow heart rate recovery (HRR) is an index of cardiac autonomic dysfunction and also a prognostic tool for cardiac and all-cause mortality in high-risk groups. In this study, we aimed to investigate the subclinical CV risk factor in different stages of CKD. Materials and Methods: Fifty-one patients with stage 1–5 CKD (mean age, 42.5±8.1 years) and 42 healthy individuals (mean age, 36.0±7.9 years) were included in the study. The HRR was calculated by subtracting the heart rates in the 1st, 2nd, and 3rd minute of the recovery period from the maximum heart rate attained during the exercise stress test. Results: The HRR in the 1st minute was significantly slower in the CKD group compared with that in the control group (22.4±11.3 and 32.4±11.1, respectively; p<0.001). The HRR in the 2nd and 3rd minute was also slower in the patient group, but the difference was not statistically significant. Seventeen patients with the 1st minute HRR ?18 beats/min were mainly distributed in CKD stages 4 and 5. Conclusion: Patients with CKD with no known cardiac disease and no structural cardiac changes were at risk of CV events with a slow HRR in the exercise test. Clinicians should be careful not to underestimate CV events in this group of patients.
dc.identifier.doi10.5152/turkjnephrol.2020.3633
dc.identifier.endpage32en_US
dc.identifier.issn1300-7718
dc.identifier.issn2667-4440
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85090649309
dc.identifier.scopusqualityQ4
dc.identifier.startpage28en_US
dc.identifier.urihttps://doi.org10.5152/turkjnephrol.2020.3633
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TkRJd05UUXhNUT09
dc.identifier.urihttps://hdl.handle.net/11491/7612
dc.identifier.volume29en_US
dc.identifier.wosWOS:000514116300006
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.institutionauthor[Belirlenecek]
dc.language.isoen
dc.relation.ispartofTurkish journal of nephrology (Online)
dc.relation.publicationcategoryDiğer
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subject[No Keywords]en_US
dc.titleSubclinical Cardiovascular Risk Factors in Chronic Kidney Disease: Abnormal Heart Rate Recovery
dc.typeOther

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