Design and rationale for the ASSOS study: appropriateness of aspirin use in medical outpatients a multicenter and observational study

dc.authorid0000-0002-8791-4475
dc.authorid0000-0002-2412-0985
dc.authorid0000-0002-2444-7523
dc.authorid0000-0002-3920-1382
dc.authorid0000-0003-1281-942X
dc.contributor.authorÇelik, Oğuzhan
dc.contributor.authorÇil, Cem
dc.contributor.authorÖzlek, Bülent
dc.contributor.authorÖzlek, Eda
dc.contributor.authorDoğan, Volkan
dc.contributor.authorBaşaran, Özcan
dc.contributor.authorDemirci, Erkan
dc.contributor.authorBekar, Lütfü
dc.contributor.authorKalçık, Macit
dc.contributor.authorKaraarslan, Osman
dc.contributor.authorYetim, Mücahit
dc.contributor.authorDoğan, Tolga
dc.contributor.authorDemir, Vahit
dc.contributor.authorKalkan, Sedat
dc.contributor.authorÖzkan, Buğra
dc.contributor.authorHidayet, Şıho
dc.contributor.authorTaylan, Gökhan
dc.contributor.authorKüçüksu, Zafer
dc.contributor.authorÇelik, Yunus
dc.contributor.authorEfe, Süleyman Çağan
dc.contributor.authorAslan, Onur
dc.contributor.authorBiteker, Murat
dc.date.accessioned2019-05-13T09:07:39Z
dc.date.available2019-05-13T09:07:39Z
dc.date.issued2018
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractObjective: The aim of this study was to describe the current status of aspirin use and the demographic characteristics of patients on aspirin for primary and secondary prevention of cardiovascular diseases. Methods: The Appropriateness of Aspirin Use in Medical Outpatients: A Multicenter, Observational Study (ASSOS) trial was a multicenter, cross-sectional, and observational study conducted in Turkey. The study was planned to include 5000 patients from 14 cities in Turkey. The data were collected at one visit, and the current clinical practice regarding aspirin use was evaluated (ClinicalTrials.gov number NCT03387384). Results: The study enrolled all consecutive patients who were admitted to the outpatient cardiology clinics from March 2018 until June 2018. Patients should be at least 18 years old, have signed written informed consent, and on aspirin (80–325 mg) therapy within the last 30 days. Cardiologists from the hospital participates in the study. Patients were divided into 2 categories according to presence or absence of atherosclerotic cardiovascular disease, namely secondary prevention group and primary prevention group, respectively. The appropriate use of aspirin in the primary and secondary prevention groups was assessed according to the European Society of Cardiology guidelines and US Preventive Services Task Force. The patients’ gastrointestinal bleeding risk factors and colorectal cancer risk were evaluated. Conclusion: The ASSOS registry will be the most comprehensive and largest study in Turkey evaluating the appropriateness of aspirin use. The results of this study help understand the potential misuse of aspirin in a real-world setting. © 2018 by Turkish Society of Cardiology.
dc.identifier.citationÇelik, O., Çil, C., Özlek, B., Özlek, E., Doğan, V., Başaran, Ö., Demirci, E., Bekar, L., Kalçık, M., Karaarslan, O., Yetim, M., Doğan, T., Demir, V., Kalkan, S., Özkan, B., Hidayet, Ş., Taylan, G., Küçüksu, Z., Çelik, Y., Efe, S. Ç., Aslan, O., Biteker, M. (2018). Design and rationale for the ASSOS study: appropriateness of aspirin use in medical outpatients a multicenter and observational study. Anatolian Journal of Cardiology, 20(6), 354-362.
dc.identifier.doi10.14744/AnatolJCardiol.2018.47587
dc.identifier.endpage362en_US
dc.identifier.issn2149-2263
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ3
dc.identifier.startpage354en_US
dc.identifier.urihttps://doi.org/10.14744/AnatolJCardiol.2018.47587
dc.identifier.urihttps://hdl.handle.net/11491/1846
dc.identifier.volume20en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherTurkish Society of Cardiology
dc.relation.ispartofAnatolian Journal of Cardiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAspirinen_US
dc.subjectOutpatientsen_US
dc.subjectPrimary Preventionen_US
dc.subjectSecondary Preventionen_US
dc.titleDesign and rationale for the ASSOS study: appropriateness of aspirin use in medical outpatients a multicenter and observational study
dc.typeArticle

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