Synthesis, characterization, antioxidant, antimicrobial and DNA binding properties of ruthenium(II), cobalt(II) and nickel(II) complexes of Schiff base containing o-vanillin
[ X ]
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer Netherlands
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, the complex combinations of Ru(II), Co(II) and Ni(II) with Schiff base obtained through the condensation of (E)-methyl 2-amino-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate with 2-hydroxy-3-methoxybenzaldehyde (o-vanillin) were prepared. The characterization of newly developed complexes was implemented by IR, elemental analyses, magnetic susceptibility, mass spectra, UV–Vis and thermogravimetry/differential thermal analysis. The X-ray powder diffraction pattern of the complexes was also investigated. The geometries of the complexes were found to be octahedral. Furthermore, antioxidant, antimicrobial and pBR322 plasmid DNA cleavage activities were investigated. The antibacterial effects of the Co(II) complex on Gram-positive and Gram-negative bacteria were identified to be higher than those of ligand. The Ru(II) complex was found to have higher radical scavenging potential on 1,1-diphenyl-2-picryl-hydrazyl (DPPH·), superoxide anion (O 2 ? ), hydroxyl (OH) and 2,2?-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) radicals, in comparison with ligand. The binding affinity of the Ni(II) complex was higher than that of ligand. © 2019, Springer Nature B.V.
Açıklama
Anahtar Kelimeler
Antimicrobial, Antioxidant, Metal Complexes, Schiff Base, X-Ray Powder Diffraction
Kaynak
Research on Chemical Intermediates
WoS Q Değeri
N/A
Scopus Q Değeri
Q2
Cilt
Sayı
Künye
Turan, N., Buldurun, K., Alan, Y., Savcı, A., Çolak, N., Mantarcı, A. (2019). Synthesis, characterization, antioxidant, antimicrobial and DNA binding properties of ruthenium (II), cobalt (II) and nickel (II) complexes of Schiff base containing o-vanillin. Research on Chemical Intermediates, 45(6), 3525-3540.
