The assessment of serum omentin levels of children with autism spectrum disorder and attention-deficit/hyperactivity disorder

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dc.authorid0000-0001-7031-3318
dc.contributor.authorYürümez, Esra
dc.contributor.authorUğur, Çağatay
dc.contributor.authorSertçelik, Mehmet
dc.date.accessioned2019-05-13T09:07:59Z
dc.date.available2019-05-13T09:07:59Z
dc.date.issued2018
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractObjectives: We aimed to investigate plasma omentin concentrations in non-obese, drug-free patients with autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) in comparison with healthy volunteers. Methods: Sixty children with ASD, 60 children with ADHD, and 60 control subjects were recruited. Plasma omentin levels were determined by the enzyme-linked immunosorbent assay. Results: Plasma levels of omentin (479.0 ng/ml) were found to be significantly higher in patients with ASD (median = 422.6, min/max; 220–800) than in controls (382.5 ng/ml) (median = 322.0, min/max 184–800). No significant difference was found between ADHD and control groups with respect to plasma omentin levels. There was no significant correlation between omentin levels and age of children, ABCL, AbBC, CARS, CPRS, and CTRS scores. Conclusions: To our knowledge, this is the first study that demonstrated the association between omentin and ASD and ADHD. The present results suggest that plasma omentin levels are increased in non-obese and drug-free patients with ASD when compared with in ADHD and healthy children. The omentin levels in ADHD and ASD need further refinement with larger samples and long-term follow-up periods. © 2018, © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
dc.identifier.citationYürümez, E., Uğur, Ç., Sertçelik, M. (2018). The assessment of serum omentin levels of children with autism spectrum disorder and attention-deficit/hyperactivity disorder. Psychiatry and Clinical Psychopharmacology, 28(3), 268-275.
dc.identifier.doi10.1080/24750573.2017.1421397
dc.identifier.endpage275en_US
dc.identifier.issn2475-0573
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ4
dc.identifier.startpage268en_US
dc.identifier.urihttps://doi.org/10.1080/24750573.2017.1421397
dc.identifier.urihttps://hdl.handle.net/11491/1915
dc.identifier.volume28en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherTaylor and Francis Ltd.
dc.relation.ispartofPsychiatry and Clinical Psychopharmacology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsAttribution 4.0 International (CC BY 4.0)*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectAdipokinesen_US
dc.subjectAttention Deficit Hyperactivity Disorderen_US
dc.subjectAutism Spectrum Disorders (ASD)en_US
dc.subjectOmentinen_US
dc.titleThe assessment of serum omentin levels of children with autism spectrum disorder and attention-deficit/hyperactivity disorder
dc.typeArticle

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