Association of prediabetes with higher coronary atherosclerotic burden among patients with first diagnosed acute coronary syndrome

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dc.contributor.authorAçar, Burak
dc.contributor.authorÖzeke, Özcan
dc.contributor.authorKarakurt, Mustafa
dc.contributor.authorÖzen, Yasin
dc.contributor.authorÖzbay, Mustafa Bilal
dc.contributor.authorÜnal, Sefa
dc.contributor.authorKaranfil, Mustafa
dc.contributor.authorYayla, Çağrı
dc.contributor.authorÇay, Serkan
dc.contributor.authorMaden, Orhan
dc.contributor.authorTopaloğlu, Serkan
dc.contributor.authorAras, Dursun
dc.contributor.authorGölbaşı, Zehra
dc.contributor.authorAydoğdu, Sinan
dc.date.accessioned2019-05-10T09:38:47Z
dc.date.available2019-05-10T09:38:47Z
dc.date.issued2019
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractDiabetes mellitus (DM) is associated with more extensive coronary atherosclerosis and more vulnerable plaque phenotypes. However, DM should not be considered a homogeneous and purely binary entity in terms of risk assessment. We evaluated the impact of prediabetic status on coronary atherosclerosis burden in patients with first-time acute coronary syndrome (ACS) who underwent urgent coronary angiography. The patients were divided into DM, prediabetes, and control groups. The 3-vessel disease (TVD) rates and SYNTAX and Gensini scoring systems for defining atherosclerotic burden were compared. The study was conducted in 469 consecutive patients admitted with a diagnosis of ACS. Of these, 250 patients were admitted at the first occurrence of ACS undergoing diagnostic coronary angiography. SYNTAX and Gensini scores and TVD rates were higher in prediabetic patients than in nondiabetic patients (P =.004, P =.008, and P =.014, respectively), but similar in prediabetic and diabetic patients (P =.912, P =.773, and P = 1.000, respectively). Coronary atherosclerosis burden is more advanced in prediabetic patients than in nondiabetic patients and is comparable between prediabetic and diabetic patients at first presentation of ACS. Cardiologists should not miss the opportunity to diagnose prediabetes and DM when patients present with an ACS. © The Author(s) 2018.
dc.identifier.citationAçar, B., Özeke, Ö., Karakurt, M.Y., Özen, Y., Özbay, M.B., Ünal, S., Karanfil, M., Çay, S., Maden, O., Topaloğlu, S.B., Aras, D., Gölbaşı, Z., Aydoğdu, S. (2018). Association of prediabetes with higher coronary atherosclerotic burden among patients with first diagnosed acute coronary syndrome. Angiology, 70(2), 174-180.
dc.identifier.doi10.1177/0003319718772420
dc.identifier.endpage180en_US
dc.identifier.issn0003-3197
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ2
dc.identifier.startpage174en_US
dc.identifier.urihttps://doi.org/10.1177/0003319718772420
dc.identifier.urihttps://hdl.handle.net/11491/474
dc.identifier.volume70en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSAGE Publications Inc.
dc.relation.ispartofAngiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAcute Coronary Syndromeen_US
dc.subjectAtherothrombosisen_US
dc.subjectCoronary Atherosclerosisen_US
dc.subjectGensini Scoreen_US
dc.subjectGlycated Hemoglobinen_US
dc.subjectHbA 1cen_US
dc.subjectPrediabetesen_US
dc.subjectSyntax Scoreen_US
dc.titleAssociation of prediabetes with higher coronary atherosclerotic burden among patients with first diagnosed acute coronary syndrome
dc.typeArticle

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