Neutrophil to lymphocyte ratio is predictor of atrial fibrillation recurrence after cardioversion with amiodarone

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dc.contributor.authorKaravelioğlu, Yusuf
dc.contributor.authorKarapınar, Hekim
dc.contributor.authorYüksel, Murat
dc.contributor.authorMemiç, Kadriye
dc.contributor.authorSarak, Taner
dc.contributor.authorKurt, Recep
dc.contributor.authorYılmaz, Ahmet
dc.date.accessioned2019-05-13T09:02:26Z
dc.date.available2019-05-13T09:02:26Z
dc.date.issued2015
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractBackground: In this study, our aim is to examine the role of the neutrophil to lymphocyte ratio (NLR) in the predictions of recurrence under long-term follow-up in patients whose sinus rhythms (SRs) were restored with amiodarone in acute atrial fibrillation (AF).Methods: Retrospectively, patients with acute AF, which successfully converted to the SR with amiodarone treatment, were recruited into the study. Patients experiencing the first AF attack were enrolled to the study and followed up for 5 years (median 23 months, 25-75 percentiles 12-24 months). Neutrophil to lymphocyte ratio was computed as absolute neutrophil count divided by lymphocyte count.Results: A total of 218 patients were recruited into the study and followed up for 21.6 ± 13.9 months; 87 (40%) patients had ?1 recurrent AF attack within this period. The follow-up of 131 (60%) patients resulted in persisted SR without any other AF attack. Groups were similar in terms of age nd gender. Left atrium (LA) diameter and NLR were increased, and platelet count and lymphocyte count were decreased in patients with AF recurrence in univariate analysis (P < .05 for all). Only LA diameter (for per mm, 1.077 [1.021-1.136], P .006) and NLR (1.584 [1.197-2.095], P .001) were independent predictors of AF recurrence in the multivariate analysis.Conclusion: Increased NLR is a marker of increased inflammation and may serve as simple, cheap, and readily available predictors of recurrence in the long-term follow-up of patients admitted with acute AF and successfully converted to SR with amiodarone. © The Author(s) 2014.
dc.identifier.citationKaravelioğlu, Y., Karapınar, H., Yüksel, M., Memiç, K., Sarak, T., Kurt, R., Yılmaz, A. (2015). Neutrophil to lymphocyte ratio is predictor of atrial fibrillation recurrence after cardioversion with amiodarone. Clinical and Applied Thrombosis/Hemostasis, 21(1), 5-9.
dc.identifier.doi10.1177/1076029613518368
dc.identifier.endpage9en_US
dc.identifier.issn1076-0296
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ2
dc.identifier.startpage5en_US
dc.identifier.urihttps://doi.org/10.1177/1076029613518368
dc.identifier.urihttps://hdl.handle.net/11491/1256
dc.identifier.volume21en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSAGE Publications Inc.
dc.relation.ispartofClinical and Applied Thrombosis/Hemostasis
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAmiodaroneen_US
dc.subjectAtrial Fibrillationen_US
dc.subjectCardioversionen_US
dc.subjectNeutrophil to Lymphocyte Ratioen_US
dc.titleNeutrophil to lymphocyte ratio is predictor of atrial fibrillation recurrence after cardioversion with amiodarone
dc.typeArticle

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