The Effects of Complete Decongestive Therapy or Intermittent Pneumatic Compression Therapy or Exercise Only in the Treatment of Severe Lipedema: A Randomized Controlled Trial

dc.contributor.authorAtan, Tuğba
dc.contributor.authorBahar Özdemir, Yeliz
dc.date.accessioned2021-11-01T15:05:30Z
dc.date.available2021-11-01T15:05:30Z
dc.date.issued2021
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractBackground: Lack of diagnostic awareness of lipedema and frequent confusion with obesity or lymphedema may be an obstacle for treatment. The clinical effects of conservative treatment methods are not clearly known. This study investigated the effects of exercise-based rehabilitation combined with complete decongestive therapy (CDT) or intermittent pneumatic compression therapy (IPCT) or alone in patients with severe lipedema. Methods: Thirty-three women with severe (type 3, stage III or IV) lipedema diagnosed according to the revised-Wold criteria were randomized into three groups: Group 1 (CDT plus exercises), Group 2 (IPCT plus exercises), and Group 3 (control-exercises alone). All groups received 30 sessions of combined (aerobic, strengthening, and stretching) exercise program. In addition, there were CDT in Group 1 and IPCT in Group 2 five times a week for 6 weeks. The primary outcome measure was the limb volume measurements. The secondary outcome measures were anthropometric measurements (body weight, body mass index, waist-to-height ratio, waist-to-hip ratio), 6-minute walk test, visual analog scale for pain, fatigue severity scale, Beck Depression Inventory, and Short Form Health Survey-36 (SF-36). Results: Thirty-one participants completed the interventions. Limb volumes (p = 0.017, eta p(2) = 0.562 for right; p < 0.001, eta p(2) = 0.775 for left), pain (p = 0.045, eta p(2) = 0.199), and physical functioning subscore of SF-36 (p = 0.040, eta p(2) = 0.465) differed significantly between treatments originating from Group 1. Conclusions: All programs improved outcome measurements after the intervention. However, when the difference between treatments was investigated, CDT administered in addition to the exercises has been shown to provide significant improvements in reducing limb volumes, pain, and physical function.
dc.identifier.citationAtan, T., & Bahar-Özdemir, Y. (2021). The Effects of Complete Decongestive Therapy or Intermittent Pneumatic Compression Therapy or Exercise Only in the Treatment of Severe Lipedema: A Randomized Controlled Trial. Lymphatic Research and Biology, 19(1), 86-95.
dc.identifier.doi10.1089/lrb.2020.0019
dc.identifier.endpage95en_US
dc.identifier.issn1539-6851
dc.identifier.issn1557-8585
dc.identifier.issue1en_US
dc.identifier.pmid33297826
dc.identifier.scopus2-s2.0-85101647813
dc.identifier.scopusqualityQ3
dc.identifier.startpage86en_US
dc.identifier.urihttps://doi.org/10.1089/lrb.2020.0019
dc.identifier.urihttps://hdl.handle.net/11491/7302
dc.identifier.volume19en_US
dc.identifier.wosWOS:000598522700001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAtan, Tuğba
dc.language.isoen
dc.publisherMary Ann Liebert, Inc
dc.relation.ispartofLymphatic Research And Biology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCompression Bandagingen_US
dc.subjectLipedemaen_US
dc.subjectManual Lymphatic Drainageen_US
dc.subjectPhysical Activityen_US
dc.titleThe Effects of Complete Decongestive Therapy or Intermittent Pneumatic Compression Therapy or Exercise Only in the Treatment of Severe Lipedema: A Randomized Controlled Trial
dc.typeArticle

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