The relationship between dual antiplatelet treatment (DAPT) score and saphenous venous grafts patency after coronary artery bypass grafting surgery

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dc.authoridKalçık, Macit / 0000-0002-8791-4475
dc.contributor.authorBayam, Emrah
dc.contributor.authorÖztürkeri, Burak
dc.contributor.authorYıldırım, Ersin
dc.contributor.authorKalçık, Macit
dc.contributor.authorKup, Ayhan
dc.contributor.authorÇakmak, Ender Özgün
dc.contributor.authorZehir, Regayip
dc.date.accessioned2021-11-01T15:06:06Z
dc.date.available2021-11-01T15:06:06Z
dc.date.issued2021
dc.departmentHitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractBackground Coronary artery bypass grafting (CABG) remains the gold standard treatment for mutivessel and left main coronary artery disease (CAD). Saphenous vein graft (SVG) patency is still a problem in CAD patients after CABG surgery. The Dual Antiplatelet Treatment (DAPT) score is a clinical prediction tool that predicts ischaemic and bleeding risk in CAD patients. The aim of this study is to investigate the relationship between DAPT score and SVG patency in CABG patients. Method This retrospective study enrolled a total of 398 patients (68 female; mean age 65.8 +/- 9.1 years) with a history of CABG surgery. The study population was divided into two subgroups according to SVG patency. The DAPT score was calculated for each patients and compared between the two groups. Results Coronary angiography revealed SVG disease in 212 patients and SVG patency in 186 patients. The rates of diabetes mellitus and hypertension, red cell distribution width values, DAPT Score, time interval after CABG and number of SVGs were significantly higher while LVEF was significantly lower in patients with SVG disease. The presence of diabetes mellitus, high DAPT score, long time interval after CABG and high number of SVGs were found to be independent predictors of SVG patency. DAPT score above 2.5 predicted SVG disease with a sensitivity of 77.1% and a specificity of 87.1% (AUC: 0.873; 95%CI: 0.823-0.924; p < 0.001). Conclusion The DAPT score may provide useful information for SVG patency in CABG patients. Patients with high DAPT score should be followed up closely for SGV occlusion. DAPT score may be useful prior to CABG in determining the duration of dual anti-platelet therapy and in encouraging the use of arterial grafts with better patency.
dc.identifier.citationBayam, E., Öztürkeri, B., Yıldırım, E., Kalçık, M., Küp, A., Çakmak, E. Ö., ... & Zehir, R. (2021). The relationship between dual antiplatelet treatment (DAPT) score and saphenous venous grafts patency after coronary artery bypass grafting surgery. Acta Cardiologica, 1-7.
dc.identifier.doi10.1080/00015385.2021.1912248
dc.identifier.endpage791en_US
dc.identifier.issn0001-5385
dc.identifier.issn1784-973X
dc.identifier.issue7en_US
dc.identifier.pmid33880976
dc.identifier.scopus2-s2.0-85104816621
dc.identifier.scopusqualityQ3
dc.identifier.startpage785en_US
dc.identifier.urihttps://doi.org/10.1080/00015385.2021.1912248
dc.identifier.urihttps://hdl.handle.net/11491/7490
dc.identifier.volume76en_US
dc.identifier.wosWOS:000642132800001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKalçık, Macit
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofActa Cardiologica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCoronary Artery Bypass Grafting (CABG)en_US
dc.subjectCoronary Artery Diseaseen_US
dc.subjectDual Antiplatelet Treatment (DAPT) Scoreen_US
dc.subjectSaphenous Venous Graft (SVG) Patencyen_US
dc.titleThe relationship between dual antiplatelet treatment (DAPT) score and saphenous venous grafts patency after coronary artery bypass grafting surgery
dc.typeArticle

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