Engineering hydrogel nanoparticles to enhance transdermal local anaesthetic delivery in human eyelid skin
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Tarih
2020
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Royal Society of Chemistry
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Herein, we focused on developing the feasibility of nano-enabled local anaesthetic (LA) delivery to anaesthetise the full thickness of eyelid skin. For this purpose a temperature-responsive hydrogel poly(Nvinylcaprolactam-co-hyaluronic acid) (p(VCL-co-HA)) was prepared through aqueous emulsion polymerization with a Food and Drug Administration (FDA) approved p(VCL) and hyaluronic acid (HA) showing remarkably high LA drug loading capacity.
Açıklama
Anahtar Kelimeler
Kaynak
RSC Advances
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
10
Sayı
7
Künye
Ozkahraman, B., Emeriewen, K., Saleh, G. M., Thanh, N. T. K. (2020). Engineering hydrogel nanoparticles to enhance transdermal local anaesthetic delivery in human eyelid skin. RSC Advances, 10(7), 3926-3930.