Engineering hydrogel nanoparticles to enhance transdermal local anaesthetic delivery in human eyelid skin

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Küçük Resim

Tarih

2020

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Royal Society of Chemistry

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Herein, we focused on developing the feasibility of nano-enabled local anaesthetic (LA) delivery to anaesthetise the full thickness of eyelid skin. For this purpose a temperature-responsive hydrogel poly(Nvinylcaprolactam-co-hyaluronic acid) (p(VCL-co-HA)) was prepared through aqueous emulsion polymerization with a Food and Drug Administration (FDA) approved p(VCL) and hyaluronic acid (HA) showing remarkably high LA drug loading capacity.

Açıklama

Anahtar Kelimeler

Kaynak

RSC Advances

WoS Q Değeri

Q2

Scopus Q Değeri

Q1

Cilt

10

Sayı

7

Künye

Ozkahraman, B., Emeriewen, K., Saleh, G. M., Thanh, N. T. K. (2020). Engineering hydrogel nanoparticles to enhance transdermal local anaesthetic delivery in human eyelid skin. RSC Advances, 10(7), 3926-3930.